Basic information
- CAS
120602-97-3- Standard SMILES
CN(O)C(=O)Cc1ccc(OCc2ccccc2)cc1- InChIKey
MYMPWMRYZURXNI-UHFFFAOYSA-N- Molecular formula
- C16H17NO3
- Average molar mass
- 271.31 g/mol
- Monoisotopic mass
- 271.1208434
Overview
structure given in first source
Names & identifiers
- Preferred name
- RG 6866
- IUPAC
- N-hydroxy-N-methyl-2-(4-phenylmethoxyphenyl)acetamide
- English name
- N-Hydroxy-N-methyl-4-benzyloxyphenylacetamide
- Molecular formula
- C16H17NO3
- Molecular weight
- 271.31
Names & synonyms
120602-97-3RG 6866Rev 6866RG-6866REV-6866DTXSID80152930RefChem:179053DTXCID20754212-(4-(Benzyloxy)phenyl)-N-hydroxy-N-methylacetamideN-Methyl-4-benzyloxyphenylacetohydroxamic acidCHEMBL54453Benzeneacetamide, N-hydroxy-N-methyl-4-(phenylmethoxy)-
Show more names
rg6866N-Hydroxy-N-methyl-4-benzyloxyphenylacetamide4-Benzyloxy-N-hydroxy-N-methylphenylacetamideN-Hydroxy-N-methyl-4-(phenylmethoxy)benzeneacetamide
2-[4-(BENZYLOXY)PHENYL]-N-HYDROXY-N-METHYLACETAMIDEN-hydroxy-N-methyl-2-(4-phenylmethoxyphenyl)acetamideorb1699531SCHEMBL2755055KUC110103NBDBM50016687AKOS000278507KSC-229-63-1
Database identifiers
- CAS
120602-97-3- PubChem CID
- 129232
- DTXSID
DTXSID80152930- ChEMBL
CHEMBL54453- Nikkaji
- J410.778K
Properties
Computed structural properties
- XLogP
- 2.2
- Topological polar surface area
- 49.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 294
Physicochemical properties
- Melting point
- 94 · 94-97°C
- Safety Statements
- 22 · 22-24/25
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- safety_code
- 22-24/25
Chemistry & industry
Applications
UsesRG 6866 is a 5-lipoxygenase (5-LOX) inhibitor with the potential to inhibit coronary artery constriction and negative cardiac inotropic effects in cardiac inflammatory states. When the heart is stimulated by antigens, RG 6866 can block the antigen-induced reduction in coronary flow in the heart.
Suppliers7 total
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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