Basic information
- CAS
106678-69-7- Standard SMILES
O=C(O)CC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)O- InChIKey
HJOWVYBCMAYCGY-NAKRPEOUSA-N- Molecular formula
- C19H27N5O12
- Average molar mass
- 517.4 g/mol
- Monoisotopic mass
- 517.16562131
Overview
consists of amino acids pGlu, Glu, Asp, Ser, Gly with pGlu at N-terminal end
Names & identifiers
- Preferred name
- Epidermal pentapeptide
- IUPAC
- (4S)-5-[[(2S)-3-carboxy-1-[[(2S)-1-(carboxymethylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid
- English name
- Pyr-Glu-Asp-Ser-Gly-OH
- Molecular formula
- C19H27N5O12
- Molecular weight
- 517.44
Names & synonyms
106678-69-7Epidermal pentapeptideEpp peptidePglu-glu-asp-ser-glyohPyroglutamyl-glutamyl-aspartyl-seryl-glycineRefChem:137197pyroGlu-Glu-Asp-Ser-GlyOH(4S)-5-[[(2S)-3-carboxy-1-[[(2S)-1-(carboxymethylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acidorb3180460DTXSID00910074Glycine, N-(N-(N-(N-(5-oxo-L-prolyl)-L-alpha-glutamyl)-L-alpha-aspartyl)-L-seryl)-(4S)-5-{[(2S)-3-Carboxy-1-({(2S)-1-[(carboxymethyl)imino]-1,3-dihydroxypropan-2-yl}imino)-1-hydroxypropan-2-yl]imino}-5-hydroxy-4-({hydroxy[(2S)-5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl]methylidene}amino)pentanoic acid
Show more names
EPPFCECHALONEPYR-GLU-ASP-SER-GLYpGlu-Glu-Asp-Ser-GlyPyr-Glu-Asp-Ser-Gly-OHL-pGlu-L-Glu-L-Asp-L-Ser-Gly-OHPYR-GLU-ASP-SER-GLY-OH USP/EP/BPL-pGlu-L-Glu-L-Asp-L-Ser-L-Gly-OH
Properties
Computed structural properties
- XLogP
- -4.6
- Topological polar surface area
- 278 Ų
- Hydrogen bond donors
- 9
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 15
- Heavy atoms
- 36
- Formal charge
- 0
- Complexity
- 907
Physicochemical properties
- storage temp.
- -15 °C · -15°C
- EWG's Food Scores
- 1 · 1
Chemistry & industry
Applications
UsesThe biological activity of PYR-GLU-ASP-SER-GLY-OH is manifested in their inhibitory effect on cell mitosis. They are tissue-specific but not species-specific, and they are also non-cytotoxic.
Upstream & downstream products
Upstream raw materials
Suppliers37 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
成都彼样生物科技有限公司18108052721 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
Chengdu Youngshe Chemical Co., Ltd.+86-18108235634 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
LEON (NANJING) BIOTECHNOLOGY CO., LTD.
Related reactions
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Compound notes
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