Basic information
- Standard SMILES
COP(=S)(S)OC- InChIKey
CZGGKXNYNPJFAX-UHFFFAOYSA-N- Molecular formula
- C2H7O2PS2
- Average molar mass
- 158.18 g/mol
- Monoisotopic mass
- 157.96250809
Overview
Dimethyldithiophosphate is an organic thiophosphate.
Names & identifiers
- Preferred name
- O,O-dimethyl phosphorodithioate
- IUPAC
- dimethoxy-sulfanyl-sulfanylidene-λ5-phosphane
- English name
- Dimethylphosphorodithioate
- Molecular formula
- C2H7O2PS2
- Molecular weight
- 158.18
Names & synonyms
756-80-9O,O-DIMETHYL DITHIOPHOSPHATEO,O-DimethyldithiophosphateDimethyl phosphorodithioateDimethyldithiophosphoric acidDimethyl phosphodithionateO,O-Dimethyl phosphorodithioateO,O-Dimethyl dithiophosphoric acidO,O-Dimethyl phosphorodithioic acid4K09JRW4Z6DTXSID5027306Kyselina O,O-dimethyldithiofosforcna
Show more names
O,O-Dimethyl S-hydrogen phosphorodithioateDMPTATHIOACIDMP-1MAPBPMAP2K1IP1U.N. 1760METHOTHIOACIDdimethyldithio
DMDTPRefChem:855038DTXCID707306212-053-9DimethylphosphorodithioateDimethyldithiophosphatePhosphorodithioic acid, O,O-dimethyl esterO,O-Dimethyl hydrogen dithiophosphate
Database identifiers
- CAS
756-80-9- PubChem CID
- 12959
- DTXSID
DTXSID5027306- ChEBI
CHEBI:166461- UNII
- 4K09JRW4Z6
- EC Number
- 212-053-9
- Nikkaji
- J2.109A
Properties
Computed structural properties
- XLogP
- 1.7
- Topological polar surface area
- 51.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 2
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 85.7
Experimental & physicochemical properties
Chemical ClassesOther Classes -> Organophosphates, Other
PesticidesEnvironmental transformation -> Pesticide transformation products (metabolite, successor)
Physicochemical properties
- Boiling point
- 65 ℃ · 65℃
- Density
- 1.29 · 1.29
- vapor pressure
- 1.33 hPa · 1.33hPa at 48.5℃
- refractive index
- 1.535 · 1.535
- storage temp.
- -20 °C · -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- clear liquid
- pka
- -0.1 · -0.10±0.30(Predicted)
- color
- Colorless to Light yellow to Red
- Water Solubility
- 226 g/L · 226g/L at 20℃
- LogP
- -0.7 at · -0.7 at 22℃
- FDA UNII
- 4 K09JRW4Z6 · 4K09JRW4Z6
- EPA Substance Registry System
- O,O-Dimethyl dithiophosphate (756-80-9)
- Symbol(GHS)
- 7 · GHS07,GHS02,GHS08,GHS05
- Signal word
- Danger
- Hazard statements
- 314 · H314-H332-H412-H290-H226-H302-H361
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P273-P501-P234-P390-P404-P201-P202-P281-P308+P313-P405-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501
- TSCA
- TSCA listed
- HS Code
- 2920.19 · 2920.19.5000
- Hazardous Substances Data
- 756 · 756-80-9(Hazardous Substances Data)
- REACH Registrations
- Active
Safety & regulation
GHS classification
GHS Classification
Danger
H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
P203, P210, P233, P234, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P318, P321, P330, P363, P370+P378, P390, P403+P235, P405, P406, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 30 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H227: Combustible liquid [Warning Flammable liquids]
Hazard information
Regulatory Information
Hazard Traits - Developmental Toxicity; Neurotoxicity
Status: Active Update: 22-11-2010 https://echa.europa.eu/registration-dossier/-/registered-dossier/10137
Hazards Summary
A human metabolite of many organophosphate pesticides; Emergency treatment: Organophosphates; [HSDB] Dialkyl phosphate metabolites are considered non-toxic and do not inhibit cholinesterase activity like their parent pesticides; May also be found in the environment as a result of organophosphate pesticide degradation; [https://www.cdc.gov/biomonitoring/pdf/OP-DPM_FactSheet.pdf] A severe eye and moderate skin irritant; Causes effects to male fertility index in repeated inhalation studies of rats; [RTECS]
Hazard Classes and Categories
Flam. Liq. 3 (100%)
Flammable liquids - Category 4
Safety & protection
Cleanup Methods
AN ORGANOPHOSPHATE CONTAINING WASTEWATER IS TREATED AT PH 5-7.5 WITH ACTIVATED SLUDGE. THUS, AN ACTIVATED SLUDGE WAS ACCLIMATIZED IN A CULTURE MEDIUM CONTAINING DIMETHYL DITHIOPHOSPHATE AMMONIUM SALT; THEN THE SLUDGE WAS USED TO TREAT A DIMETHYL DITHIOPHOSPHATE CONTAINING WASTEWATER. THE TOTAL ORG C OF 83-87 PPM WAS REDUCED TO 17-19 PPM AFTER 12 HR OF TREATMENT.
THE ACTIVATED SLUDGE WAS ACCLIMATED TO O,O-DIMETHYL PHOSPHORODITHIOATE BY THE FILL & DRAW METHOD. THE ACCLIMATED, ACTIVATED SLUDGE DEGRADE 500 MG/L IN 7 HR. THE PH OF THE MIXED LIQUOR WAS ADJUSTED TO DEGRADE O,O-DIMETHYL PHOSPHORODITHIOATE & THE OPTIMUM PH WAS 6.5-7.0.
Toxicology
Environmental FateO,O-DIMETHYL DITHIOPHOSPHATE IS PRODUCED AS METABOLITE FROM MANY ORGANOPHOSPHATE INSECTICIDES IN SOIL... EXAMPLES OF SUCH ORGANOPHOSPHATES ARE PHENTHOATE, MALATHION, DIMETHOATE, & SUPRACIDE.
Effluent ConcentrationsO,O-DIMETHYL PHOSPHORODITHIOATE IS A PRECURSOR IN THE PRODUCTION OF SUCH ORGANOPHOSPHORUS PESTICIDES AS MALATHION, DIMETHOATE, ETC, & IS ABUNDANT IN WASTE-WATER OF PESTICIDE MFR.
Probable Routes of Human ExposureDIMETHYL PHOSPHATE & ITS THIODERIVATIVES WERE EXCRETED IN URINE OF HUMANS AFTER OCCUPATIONAL EXPOSURE TO ORGANOPHOSPHORUS PESTICIDES.
Toxicity DataLC50 (rat) = 1,700 mg/m3/4h
Safety data
- tsca
- TSCA listed
- hs_code
- 2920.19.5000
- Signal word
- Danger
- Symbol(GHS)
- GHS07,GHS02,GHS08,GHS05
- Hazard statements
- H314-H332-H412-H290-H226-H302-H361
- REACH Registrations
- Active
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P273-P501-P234-P390-P404-P201-P202-P281-P308+P313-P405-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501
- Hazardous Substances Data
- 756-80-9(Hazardous Substances Data)
Chemistry & industry
Pharmacology
Metabolism/MetabolitesO,O-DIMETHYL DITHIOPHOSPHATE IS PRODUCED AS METABOLITE FROM MANY ORGANOPHOSPHATE INSECTICIDES IN...PLANTS /&/ ANIMALS... EXAMPLES OF SUCH ORGANOPHOSPHATES ARE PHENTHOATE, MALATHION, DIMETHOATE, & SUPRACIDE.
Absorption, Distribution and ExcretionIN THE UNITED STATES ON A NATIONAL BASIS FOR FISCAL YEAR 1970-74 ANALYSIS OF 267 URINE SAMPLES FROM GENERAL POPULATION REVEALED THE PRESENCE OF DIALKYL PHOSPHATE.
Uses & manufacturing
Uses
Used to make insecticides such as malathion, azinphos-methyl, phosmet, and methidathion; [HSDB]
CHEM INT FOR MALATHION (INSECTICIDE)
CHEM INT FOR AZINPHOS-METHYL (INSECTICIDE)
CHEM INT FOR PHOSMET (INSECTICIDE)
CHEM INT FOR METHIDATHION (INSECTICIDE)
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
(1978) 7.0X10+9 G-EST PRODN FOR PESTICIDE USE
(1982) 7.0X10+9 G-EST PRODN FOR PESTICIDE USE
Consumption PatternsESSENTIALLY 100% AS A CHEM INT FOR INSECTICIDES
Methods of ManufacturingREACTION OF PHOSPHOROUS PENTASULFIDE WITH METHYL ALCOHOL
Use ClassificationEnvironmental transformation -> Pesticide transformation products (metabolite, successor)
General Manufacturing Information
Phosphorodithioic acid, O,O-dimethyl ester: INACTIVE
A SAMPLE OF TECHNICAL GRADE MALATHION CONTAINED O,O-DIMETHYL DITHIOPHOSPHATE.
Applications
UsesO,O'-Dimethyl Dithiophosphate can be used as a pesticide intermediate, mainly for the preparation of organophosphorus pesticides such as dimethoate and malathion.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers50 total
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]
湖北盛明安化工有限公司13928406992 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
苏州市森菲达化工有限公司18796480002 18796480002 · [email protected]
杭州鼎燕化工有限公司13588754826 13588754826 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海钰康生物科技有限公司18939844854 · [email protected]
维赛诺化学技术（北京）有限公司13811761079 · [email protected]
湖北广奥生物科技有限公司027-02702759223056 18162699093 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
湖北成海化工有限公司027-59220433 18327245847 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
Xiamen AmoyChem Co., Ltd+86-86-5926051114 · [email protected]
ZHEJIANG JIUZHOU CHEM CO., LTD+86-0576225566889 +86-13454675544 · [email protected]；[email protected]；[email protected]
广东元丰化学试剂有限公司0751-2829979 13376591640 · [email protected]
淄博润恒生物科技有限公司13561657928 13561657928 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
武汉弘德悦欣医药科技有限公司027-83855396 15271852016
盖米科技（青岛）有限公司19524370118 · [email protected]
湖北巨胜科技有限公司027-59599241 18871490274 · [email protected]
湖北源梦生物科技有限公司027-68897569 18120462897 · [email protected]
上海昕凯医药科技有限公司21-619849051-1 18521059765 · [email protected]
南京安研生物科技有限公司025-52151215 13915956535 13915956535 · [email protected]
北京禾兴源科技有限公司18511709189 · [email protected]
湖北军瑞生物科技有限公司13971166412 · [email protected]
武汉峰耀同辉化学制品有限公司027-87466205 15377579727 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
湖北川合化工有限公司187-7130-7593 18672969259 · [email protected]
艾吉析科技（上海）有限公司17721401538;17717235263 17721401538 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
湖北万业众诚化学试剂有限责任公司18671296875 · [email protected]
湖北源梦生物科技有限公司027-68897569 18120462897 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
上海岚克医药科技发展有限公司0086-21-58956006
南通市苏北化工原料有限公司0513-85290972 18762756250 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
Additional notes
DefinitionChEBI: Dimethyldithiophosphate is an organic thiophosphate.
Related reactions
9 records
Linked notes
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