Basic information
- CAS
6000-43-7- Standard SMILES
Cl.[NH3+]CC(=O)[O-]- InChIKey
IVLXQGJVBGMLRR-UHFFFAOYSA-N- Molecular formula
- C2H6ClNO2
- Average molar mass
- 111.53 g/mol
- Monoisotopic mass
- 111.0087061
Overview
See also: Glycine Hydrochloride (preferred); Glycine (has active moiety).
Names & identifiers
- Preferred name
- Glycinebetaine hydrochloride
- IUPAC
- 2-azaniumylacetate;hydrochloride
- English name
- Glycine hydrochloride
- Molecular formula
- C2H6ClNO2
- Molecular weight
- 111.53
Names & synonyms
glycinebetaine hydrochlorideGLYCINE HCLGLYCINE-HCL BUFFERAMINOACETIC ACID HYDROCHLORIDEGly.HCLh-gly-oh.hclycine hydrochLGLYCINE HYDROCHLORIDEAmino-acetic acid HClGlycocol hydrochlorideGLYCOCOLL HYDROCHLORIDE
Database identifiers
- CAS
6000-43-7、7490-95-1- PubChem CID
- 129690804
Properties
Computed structural properties
- Topological polar surface area
- 67.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 37.4
Physicochemical properties
- Melting point
- 176 · 176-180 °C(lit.)
- Density
- 1.457 · 1.457[at 20℃]
- vapor pressure
- 0.003 Pa · 0.003Pa at 20℃
- storage temp.
- 2 · 2-8°C
- form
- Crystalline Powder
- color
- White to almost white
- biological source
- synthetic
- Water Solubility
- SLIGHTLY SOLUBLE
- Sensitive
- Hygroscopic
- Merck
- 14 · 14,4491
- BRN
- 3909617 · 3909617
- Major Application
- food and beverages
- Cosmetics Ingredients Functions
- BUFFERING
- InChI
- InChI=1S/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H
- InChIKey
- IVLXQGJVBGMLRR-UHFFFAOYSA-N
- SMILES
- C(=O)(O)CN.Cl
- LogP
- -3.25 at · -3.25 at 20℃
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 10
- wgk
- 2
- tsca
- TSCA listed
- rtecs
- MC0560000
- ridadr
- UN 1789 8/PG 3
- hs_code
- 29224999
- risk_code
- 22
- Signal word
- Danger
- Symbol(GHS)
- GHS05
- safety_code
- 24/25-44
- Storage Class
- 8B - Non-combustible corrosive hazardous materials
- Hazard statements
- H314
- REACH Registrations
- Active
- Hazard Classifications
- Eye Irrit. 2Met. Corr. 1Skin Irrit. 2
- Precautionary statements
- P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Chemistry & industry
Applications
UsesGlycine hydrochloride is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.Glycine Hydrochloride is commonly used in buffer solutions, in electrophoresis, and preparative chromatography.
Preparation methods
PreparationGlycine hydrochloride can be prepared by the action of hydrochloric acid on hippuric acid,aminoacetonitrile,methyleneaminoacetonitrile, and on ethyl phthaliminoacetate. Aniline has been recommended for its conversion into free glycine. Glycine can also be prepared by the interaction of chloroacetic acid and ammonia; by the hydrolysis of methyleneaminoacetonitrile by successive treatments with barium hydroxide and sulfuric acid; and by the hydrolysis of aminoacetonitrile by means of barium hydroxide. A thorough study has been reported for its preparation in improved yields by the sulfuric acid hydrolysis of aminoacetonitrile, and in satisfactory yields from chloroacetic acid and ammonia. Other methods of preparation include the reduction of cyanoformic esters, a modified Curtius degradation of ethyl cyanoacetate, and the hydrolysis of the neck ligaments of cattle.synthesis of Glycine hydrochloride
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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