Basic information
- CAS
122299-11-0- Standard SMILES
CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)O- InChIKey
AHWKRDTXAJKKKX-WWRYCTMDSA-N- Molecular formula
- C48H78N12O15
- Average molar mass
- 1,063.2 g/mol
- Monoisotopic mass
- 1,062.57095983
Names & identifiers
- Preferred name
- Eglin c (41-49)
- IUPAC
- (3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]butanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid
- English name
- EGLIN C (41-49)
- Molecular formula
- C48H78N12O15
- Molecular weight
- 1063.22
Names & synonyms
Eglin c (41-49)122299-11-0Ser-pro-val-thr-leu-asp-leu-arg-tyr-OHDTXSID40153564RefChem:136357DTXCID4076055C48H78N12O15MFCD00676937DA-73044FE108681(3S)-4-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-1-carboxy-2-hydroxy-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]carbamoyl]-3-methyl-butyl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]butanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoic acidL-Prolyl-L-valyl-L-threonyl-L-leucyl-L-alpha-aspartyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-tyrosyl-L-serine
Show more names
SPVTLDLRYSER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYRH-SER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYR-OHSER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYR: SPVTLDLRYL-Tyrosine, L-seryl-L-prolyl-L-valyl-L-threonyl-L-leucyl-L-α-aspartyl-L-leucyl-L-arginyl-
Properties
Computed structural properties
- XLogP
- -3.3
- Topological polar surface area
- 445 Ų
- Hydrogen bond donors
- 16
- Hydrogen bond acceptors
- 17
- Rotatable bonds
- 32
- Heavy atoms
- 75
- Formal charge
- 0
- Complexity
- 1,980
Physicochemical properties
- Density
- 1.44 · 1.44±0.1 g/cm3(Predicted)
- storage temp.
- -15 °C · -15°C
- form
- Solid
- pka
- 3.07 · 3.07±0.10(Predicted)
- color
- White to off-white
Chemistry & industry
Applications
UsesEglin c (41-49) is a peptide fragment related to eglin c. Eglin c (41-49) shows inhibitory effects to cathepsin G and α-chymotrypsin with Ki values of 42 and 20 μM, respectively[1].
Suppliers45 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
Chengdu Youngshe Chemical Co., Ltd.+86-18108235634 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
LEON (NANJING) BIOTECHNOLOGY CO., LTD.15051830413 · [email protected]
Moxin Chemicals+86-17320513646 +86-17320513646 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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