Sut 8701

HCID 130002

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Basic information

CAS: 123577-73-1
Standard SMILES: CCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC(=O)OP(C)(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey: AHBONLSOQLMUGB-WGXSSYHUSA-N
Molecular formula: C54H74N9O13P
Average molar mass: 1,088.2 g/mol
Monoisotopic mass: 1,087.51437045

Overview

prevents the cholinergic degeneration in the rat cerebral cortex following basal forebrain lesioning; may be effective in slowing down the degenerative processes in Alzheimer'sdisease; structure given in first source

Names & identifiers

Preferred name: Sut 8701
IUPAC: dimethylphosphoryl (3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-oxobutanoate

Names & synonyms

Sut 8701123577-73-1Sut-8701DTXSID70154044N-((1,1-Dimethylethoxy)carbonyl)-O-(dimethylphosphinyl)-tyrosyl-norleucylglycyl-tryptophyl-norleucyl-aspartyl-phenylalaninamideL-Phenylalaninamide, N-((1,1-dimethylethoxy)carbonyl)-O-(dimethylphosphinyl)-L-tyrosyl-L-norleucylglycyl-L-tryptophyl-L-norleucyl-L-alpha-aspartyl-RefChem:186848DTXCID1076535dimethylphosphoryl (3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-oxobutanoateN-((1,1-Dimethylethoxy)carbonyl) O-(dimethylphosphinyl)-tyr-nle-gly-trp-nle-asp-phe-NH2SCHEMBL194796N-(tert-Butoxycarbonyl)-L-tyrosyl-L-norleucylglycyl-L-tryptophyl-L-norleucyl-O-(dimethylphosphoryl)-4-oxo-L-homoseryl-L-phenylalaninamide

Database identifiers

CAS: 123577-73-1
PubChem CID: 130002
DTXSID: DTXSID70154044

Properties

Computed structural properties

XLogP: 4.3
Topological polar surface area: 335 Å²
Hydrogen bond donors: 10
Hydrogen bond acceptors: 13
Rotatable bonds: 32
Heavy atoms: 77
Formal charge: 0
Complexity: 2,040

Related reactions

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Compound notes

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