2-Methylpyrrolidine (HCID 13003)

Overview

2-methylpyrrolidine is a member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. It has a role as a plant metabolite.

Names & identifiers

Preferred name: 2-Methylpyrrolidine
IUPAC: 2-methylpyrrolidine
English name: 2-Methylpyrrolidine
Molecular formula: C5H11N
Molecular weight: 85.15

Names & synonyms

2-METHYLPYRROLIDINE765-38-8Pyrrolidine, 2-methyl-CHEBI:145240DTXSID70883347RefChem:88382DTXCID70869429212-144-3MFCD000144912-methyl pyrrolidine2-Methyl-pyrrolidine2-methylpyrolidine

Show more names

RMA-5592-methyl-pyrrolidin2-MethylpyrrolidineHCl2-methyl-1-pyrrolidine2-Methylpyrrolidine,98%2-Methylpyrrolidine, 98% 2GRHydroxychloroquine Impurity 16Hydroxychloroquine Impurity 56

2-methylpyrroldine2-methyl-pyrolidineEINECS 212-144-3rac-2-methyl-pyrrolidinerac.-2-methylpyrrolidine2-(RS)-methylpyrrolidineracemic 2-methylpyrrolidine2-Methylpyrrolidine, 96%

Database identifiers

CAS: 765-38-8
PubChem CID: 13003
DTXSID: DTXSID70883347
ChEBI: CHEBI:145240
EC Number: 212-144-3
Nikkaji: J193.131H

Properties

Computed structural properties

XLogP: 0.7
Topological polar surface area: 12 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 1
Rotatable bonds: 0
Heavy atoms: 6
Formal charge: 0
Complexity: 43.2

Physicochemical properties

Melting point: -96.37 °C · -96.37°C (estimate)
Boiling point: 97 · 97-99 °C/744 mmHg (lit.)
Density: 0.834 g/mL · 0.834 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.437(lit.)
Flash point: 37 °F · 37 °F
storage temp.: -20 °C · Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka: 10.93 · 10.93±0.10(Predicted)
form: Liquid
color: Clear colorless to light yellow
Water Solubility: soluble
InChI: InChI=1S/C5H11N/c1-5-3-2-4-6-5/h5-6H,2-4H2,1H3
InChIKey: RGHPCLZJAFCTIK-UHFFFAOYSA-N
SMILES: N1CCCC1C
CAS DataBase Reference: 765 · 765-38-8(CAS DataBase Reference)
NIST Chemistry Reference: 2 · 2-Methylpyrrolidine(765-38-8)
EPA Substance Registry System: 2 · Pyrrolidine, 2-methyl- (765-38-8)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS05,GHS07
Signal word: Danger
Hazard statements: 225 · H225-H302-H314
Precautionary statements: 210 · P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
PPE: 95 · dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes: F,C
Risk Statements: 11 · 11-34-22
Safety Statements: 16 · 16-26-36/37/39-45
RIDADR: 2924 · UN 2924 3/PG 2
WGK Germany: 3 · 3
TSCA: TSCA listed
HazardClass: 3 · 3
PackingGroup: II
HS Code: 29339900 · 29339900
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 4 OralEye · Acute Tox. 4 OralEye Dam. 1Flam. Liq. 2Skin Corr. 1B

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationChemical: Pyrrolidine, 2-methyl-

Other Safety InformationEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia

Hazard Classes and CategoriesFlam. Liq. 2 (100%)

Safety data

PPE: dust mask type N95 (US), Eyeshields, Gloves
wgk: 3
tsca: TSCA listed
ridadr: UN 2924 3/PG 2
hs_code: 29339900
risk_code: 11-34-22
Signal word: Danger
Symbol(GHS): GHS02,GHS05,GHS07
hazard_code: F,C
safety_code: 16-26-36/37/39-45
hazard_class: 3
Storage Class: 3 - Flammable liquids
packing_group: II
Hazard statements: H225-H302-H314
Hazard Classifications: Acute Tox. 4 OralEye Dam. 1Flam. Liq. 2Skin Corr. 1B
Precautionary statements: P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationPyrrolidine, 2-methyl-: INACTIVE

Applications

Uses2-Methylpyrrolidine can be used to produce2-(2-methylpyrrolidinyl)benzaldehydeat the temperature of152°C. It is commonly used as organic reagent.

General Description2-Methylpyrrolidine is a substituted pyrrolidine. It is one of the major bioactive compounds found in Teucrium manghuaense. The hydrodenitrogenation of 2-methylpyrrolidine in the presence of sulfided NiMo/γ-Al2O3 catalyst has been studied.

Upstream & downstream products

Downstream products

1-Ethyl-2-methylpyrrolidine

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]

Sichuan Biosynce Pharmatech Co., Ltd.[email protected]

湖北瑞玛标物科技有限公司15787879035 15787875101 · [email protected]

Additional notes

DefinitionChEBI: 2-methylpyrrolidine is a member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. It has a role as a plant metabolite.