Sdz 62-434
Basic information
- CAS
115621-95-9- Standard SMILES
C1=C(c2ccc(N3CCCCC3)cc2)N2CCN=C2c2ccccc21.Cl.Cl- InChIKey
BKOQATFPPHQOQH-UHFFFAOYSA-N- Molecular formula
- C22H25Cl2N3
- Average molar mass
- 402.4 g/mol
- Monoisotopic mass
- 401.1425532
Overview
may be an inhibitor of signal transduction in cancer cells; structure given in first source; PAF antagonist
Names & identifiers
- Preferred name
- Sdz 62-434
- IUPAC
- 5-(4-piperidin-1-ylphenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline;dihydrochloride
- English name
- SDZ 62-434
- Molecular formula
- C23H25N3.2ClH
- Molecular weight
- 416.393
Names & synonyms
115621-95-9Sdz 62-434DTXSID50151152Imidazo(2,1-a)isoquinoline, 2,3-dihydro-5-(4-(1-piperidinylmethyl)phenyl)-, dihydrochlorideRefChem:182091DTXCID2073643SDZ-62-4342,3-Dihydro-5-(4-(1-piperidinylmethyl)phenyl)imidazo(2,1-a)isoquinoline dihydrochloride5-(4-piperidin-1-ylphenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline;dihydrochlorideImidazo[2,1-a]isoquinoline, 2,3-dihydro-5-[4-(1-piperidinylmethyl) phenyl]-, hydrochloride (1:2)5-(4'-Piperidinomethylphenyl)-2,3-dihydroimidazo(2,1-a)isochinolin-dihydrochlorid [German]Imidazo(2,1-a)isoquinoline, 2,3,-dihydro-5-(4-(1-piperidinyl)phenyl)-, dihydrochloride
Show more names
SCHEMBL294614475-(4'-Piperidinomethylphenyl)-2,3-dihydroimidazo(2,1-a)isochinolin-dihydrochlorid5-(4-(piperidin-1-yl)phenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline dihydrochlorideBS1774385-[4-(Piperidin-1-yl)phenyl]-2,3-dihydroimidazo[2,1-a]isoquinoline--hydrogen chloride (1/2)
Database identifiers
- CAS
115621-95-9- PubChem CID
- 130786
- DTXSID
DTXSID50151152
Properties
Computed structural properties
- Topological polar surface area
- 18.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 27
- Formal charge
- 0
- Complexity
- 537
Physicochemical properties
- Melting point
- 317 · 317-320 °C
Chemistry & industry
Applications
UsesSDZ-62-434 is a platelet-activating factor (PAF) antagonist. SDZ-62-434 has antiproliferative activity in human solid and haematological malignancies[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…