Basic information
- CAS
789-02-6- Standard SMILES
Clc1ccc(C(c2ccccc2Cl)C(Cl)(Cl)Cl)cc1- InChIKey
CVUGPAFCQJIYDT-UHFFFAOYSA-N- Molecular formula
- C14H9Cl5
- Average molar mass
- 354.5 g/mol
- Monoisotopic mass
- 351.914689
Overview
o,p'-DDT can cause developmental toxicity, female reproductive toxicity and male reproductive toxicity according to The National Institute for Occupational Safety and Health (NIOSH) and The Environmental Protection Agency (EPA).
Names & identifiers
- Preferred name
- O,P'-Ddt
- IUPAC
- 1-chloro-2-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene
- English name
- 2,4'-DDT
- Molecular formula
- C14H9Cl5
- Molecular weight
- 0
Names & synonyms
O,P'-DDT789-02-62,4'-DDTortho,para'-DDTo,p-DdtDTXSID60223451,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1,1-trichloroethane1-Chloro-2-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene2,2,2,o,p'-PentachloroethylidenebisbenzeneD4K93Z1TBH2,2-Bis(o,p-chlorophenyl)-1,1,1-trichloroethane
Show more names
Ethane, 1,1,1-trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-o,p'-dichlorodiphenyltrichloroethaneNSC-33446NSC-57644O,P'-CHLOROPHENOTHANEDTXCID0023451-Chloro-2-(2,2,2-trichloro-1-(4-chlorophenyl)ethyl)benzene1,1,1-trichloro-2-(2-chlorophenyl)-2-(4-chlorophenyl)ethane
Database identifiers
- CAS
789-02-6- PubChem CID
- 13089
- DTXSID
DTXSID6022345- ChEMBL
CHEMBL364900- ChEBI
CHEBI:34027- UNII
- D4K93Z1TBH
Properties
Computed structural properties
- XLogP
- 6.7
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 2
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 280
Experimental & physicochemical properties
SpringerMaterials PropertiesBoiling point
PesticidesOrganochlorine pesticide
LogP5.53
Endocrine DisruptorsPotential endocrine disrupting compound
Physicochemical properties
- Toxicity
- 10 mg/kg · dns-rat-ipr 10 mg/kg JTEHD6 16,493,85
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P203, P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P318, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 55 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Hazard Traits - Carcinogenicity; Developmental Toxicity; Endocrine Toxicity; Hepatotoxicity and Digestive System Toxicity; Neurotoxicity; Reproductive Toxicity
Benzene, 1-chloro-2-2,2,2-trichloro-1-(4-chlorophenyl)ethyl-: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Benzene, 1-chloro-2-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]-: Human health tier I assessment
Hazard Classes and CategoriesAcute Tox. 3 (100%)
Toxicology
TreatmentTreatment of DDT exposure should be primarily directed towards decontamination and supportive care, as there is no specific antidote. The use of gastric lavage and activated charcoal for large ingestions may be effective. (L140)
Health Effects
Exposure to DDT causes loss of weight and anorexia. DDT poisoning affects CNS function in humans, but pathologic changes are observed in the liver and reproductive organs. Hypertrophy of hepatocytes and subcellular organelles such as mitochondria, proliferation of smooth endoplasmic reticulum, centrolobular necrosis after exposure to high concentrations, and an increase in the incidence of hepatic tumors have been noted. (T10)
Chemistry & industry
Pharmacology
Metabolism/Metabolites
DDT is absorbed in the stomach and intestine, after which it enters the lymphatic system and is carried throughout the body and incorporated into fatty tissues. Metabolism of DDT occurs mainly via cytochrome P-450 enzymes in the liver and kidney, where it undergoes reductive dechlorination to DDD (dichlorodiphenyldichloroethane) and DDE (dichlorodiphenyldichloroethylene). These compounds are further degraded into additional metabolites, mainly DDA (bis(p-chlorophenyl) acetic acid), which are excreted in the urine. (L85)
MeSH Pharmacological ClassificationNon-steroidal compounds with estrogenic activity.
Uses & manufacturing
UsesDDT is used as a pesticide and in disease vector control. (L84)
Suppliers50 total
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
盐城通铭生物科技有限公司15195160625 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
江苏智芯廷科技有限公司18221391031 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
梯希爱（上海）化工贸易有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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