Basic information
- CAS
137018-54-3- Standard SMILES
Cc1cc(O)cc2cc3c(c(O)c12)C(=O)CCC3O- InChIKey
LIETVYHJBSLSSW-UHFFFAOYSA-N- Molecular formula
- C15H14O4
- Average molar mass
- 258.27 g/mol
- Monoisotopic mass
- 258.08920892
Overview
structure given in first source; isolated from Streptomyces sp. KO-3599
Names & identifiers
- Preferred name
- Okicenone
- IUPAC
- 4,6,9-trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one
- English name
- okicenone
- Molecular formula
- C15H14O4
- Molecular weight
- 258.27
Names & synonyms
Okicenone137018-54-34,6,9-Trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one3,4-Dihydro-4,6,9-trihydroxy-8-methyl-1(2H)-anthracenone1(2H)-Anthracenone, 3,4-dihydro-4,6,9-trihydroxy-8-methyl-RefChem:168044CHEMBL1240971orb1699783SCHEMBL17866977SCHEMBL29494799DTXSID80929664BDBM50326011
Show more names
3,4-Dihydro-4,6,9-trihydroxy-8-methylanthracen-1(2H)-one
AKOS040749061DA-76393HY-101112CS-0020875T282284,6,9-Trihydroxy-8-methyl-3,4-dihydroanthracen-1(2H)-one
Database identifiers
- CAS
137018-54-3- PubChem CID
- 132015
- DTXSID
DTXSID80929664- ChEMBL
CHEMBL1240971- Nikkaji
- J431.078K
Properties
Computed structural properties
- XLogP
- 2.4
- Topological polar surface area
- 77.8 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 0
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 369
Chemistry & industry
Applications
DescriptionOkicenone is an antibiotic, interferring with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation.
UsesOkicenone is a Hu protein R (HuR) inhibitor. Okicenone inhibits HuR oligomerization, interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation[1].
Suppliers3 total
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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