Basic information
- CAS
834-14-0- Standard SMILES
COc1ccc(Cc2ccccc2)cc1- InChIKey
GQLYCRTUQGSDSM-UHFFFAOYSA-N- Molecular formula
- C14H14O
- Average molar mass
- 198.26 g/mol
- Monoisotopic mass
- 198.10446507
Overview
augments activity of leukotriene A(4) hydrolase
Names & identifiers
- Preferred name
- 4-Methoxydiphenylmethane
- IUPAC
- 1-benzyl-4-methoxybenzene
- English name
- 4-Methoxydiphenylmethane
- Molecular formula
- C14H14O
- Molecular weight
- 198.26
Names & synonyms
1-BENZYL-4-METHOXYBENZENE4-Methoxydiphenylmethane834-14-0Anisole, p-benzyl-Benzene, 1-methoxy-4-(phenylmethyl)-p-Methoxydiphenylmethanep-MethoxyphenylphenylmethaneDTXSID70232316NSC 2413RefChem:99643DTXCID70154807GQLYCRTUQGSDSM-UHFFFAOYSA-N
Show more names
4-MDM >=98% (HPLC)p-Anisylphenylmethane4-METHOXYDIPHENYLMETHANE 98%
InChI=1/C14H14O/c1-15-14-9-7-13(8-10-14)11-12-5-3-2-4-6-12/h2-10H,11H2,1Hp-Benzylanisole4-MDM4-BenzylanisoleMFCD000940721-benzyl-4-methoxy-benzene4-methoxy-1-benzylbenzene(4-Methoxyphenyl)phenylmethane
Database identifiers
- CAS
834-14-0- PubChem CID
- 13264
- DTXSID
DTXSID70232316- ChEMBL
CHEMBL1915868- EC Number
- 674-157-4
- Nikkaji
- J145.239H
Properties
Computed structural properties
- XLogP
- 3.8
- Topological polar surface area
- 9.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 3
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 164
Experimental & physicochemical properties
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
Physicochemical properties
- Density
- 1 · 1,05 g/cm3
- storage temp.
- Sealed in dry,Room Temperature
- form
- oil (Low melting solid)
- color
- colorless
- Symbol(GHS)
- 5 · GHS05,GHS09
- Signal word
- Danger
- Hazard statements
- 315 · H315-H318-H400
- Precautionary statements
- 273 · P273-P280-P305+P351+P338
- Hazard Codes
- Xi,N
- Risk Statements
- 36 · 36/37/38-50/53-41-37/38
- Safety Statements
- 26 · 26-36/37/39-61-60-39
- RIDADR
- 3077 · UN 3077 9 / PGIII
- WGK Germany
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P273, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- wgk
- 3
- ridadr
- UN 3077 9 / PGIII
- risk_code
- 36/37/38-50/53-41-37/38
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS09
- hazard_code
- Xi,N
- safety_code
- 26-36/37/39-61-60-39
- Hazard statements
- H315-H318-H400
- Precautionary statements
- P273-P280-P305+P351+P338
Chemistry & industry
Applications
Uses4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the Leukotriene A4 Hydrolase (LTA4H) aminopeptidase enzyme activity. 4-MDM reduces the neutrophil recruitment in the lung by enhancing the degradation of proline-glycine-proline by LTA4H, thereby reducing inflammation, and does not affect the epoxy-hydrolase activity of LTA4H. 4-MDM can be used for research on lung diseases[1].
Suppliers33 total
北京福源坊科技有限公司010-57903446 15869909019 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海炎泽化工有限公司15345144255 19975051755 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
苏州市森菲达化工有限公司18796480002 18796480002 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
武汉凯威斯科技有限公司86-027-67849912 · [email protected]
上海泰坦科技股份有限公司4006009262 13023226327 · [email protected]
山东李比希生物医药科技有限公司15318973357; 15318973357 · [email protected]
Related reactions
1 records
Compound notes
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