Ripisartan
Basic information
- CAS
148504-51-2- Standard SMILES
CCCc1nc(C)n2[nH]c(=O)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1- InChIKey
OLJAPHMBAMBVKL-UHFFFAOYSA-N- Molecular formula
- C23H22N8O
- Average molar mass
- 426.5 g/mol
- Monoisotopic mass
- 426.19165736
Overview
Ripisartan is a small molecule drug. The usage of the INN stem '-sartan' in the name indicates that Ripisartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). Ripisartan has a monoisotopic molecular weight of 426.19 Da.
Names & identifiers
- Preferred name
- Ripisartan
- IUPAC
- 5-methyl-7-propyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-[1,2,4]triazolo[1,5-c]pyrimidin-2-one
- English name
- Ripisartan
- Molecular formula
- C23H22N8O
- Molecular weight
- 426.47
Names & synonyms
RipisartanRipisartan [INN]UP 269-6UNII-7LQ7OQP6537LQ7OQP6535-Methyl-7-propyl-8-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-(1,2,4)triazolo(1,5-c)pyrimidin-2(3H)-oneRIPISARTAN [WHO-DD]DTXSID101640015-Methyl-7-propyl-8-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-s-triazolo(1,5-c)pyrimidin-2(3H)-one(1,2,4)Triazolo(1,5-c)pyrimidin-2(3H)-one, 5-methyl-7-propyl-8-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-ripisartanumRefChem:179486
Show more names
[1,2,4]Triazolo[1,5-c]pyrimidin-2(3H)-one, 5-methyl-7-propyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
DTXCID8086492148504-51-25-methyl-7-propyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-[1,2,4]triazolo[1,5-c]pyrimidin-2-oneCHEMBL312104UP26965-Methyl-7-n-propyl-8-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-(1,2,4)-triazolo(1,5-c)pyrimidin-2(3H)-oneUP-2696UP-269-6
Properties
Computed structural properties
- XLogP
- 3
- Topological polar surface area
- 112 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 813
Physicochemical properties
- FDA UNII
- 7 LQ7OQP653 · 7LQ7OQP653
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesRipisartan (UP-2696) is an angiotensin II receptor antagonist. Ripisartan is orally available. Ripisartan binds to angiotensin II receptors, dilates blood vessels, and lowers blood pressure[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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