neuropeptide DF2
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Basic information
- CAS
149471-11-4- Standard SMILES
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O- InChIKey
DWSQPUHNGRSXSJ-MRNVWEPHSA-N- Molecular formula
- C44H67N15O10
- Average molar mass
- 966.1 g/mol
- Monoisotopic mass
- 965.51953339
Overview
an FMRFamide-related neuropeptide from crayfish, Procambarus clarkii
Names & identifiers
- Preferred name
- neuropeptide DF2
- IUPAC
- (3S)-3-amino-4-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
- English name
- ASP-ARG-ASN-PHE-LEU-ARG-PHE AMIDE*TRIFLUOROACETATE
- Molecular formula
- C44H67N15O10
- Molecular weight
- 966.1
Names & synonyms
Neuropeptide DF2Drnflrfamide149471-11-4DF(2) NeuropeptideAsp-arg-asn-phe-leu-arg-phe-NH2DF2 neuropeptideAspartyl-arginyl-asparaginyl-phenylalanyl-leucyl-arginyl-phenylalaninamideDTXSID40164276RefChem:165575DTXCID0086767(3S)-3-amino-4-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acidL-alpha-Aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide
Show more names
neuropeptidedf2asp-arg-asn-phe-leu-arg-phe amide*trifluoroacetatASP-ARG-ASN-PHE-LEU-ARG-PHE AMIDE*TRIFLUOROACETATEAsp-Arg-Asn-Phe-Leu-Arg-Phe amide trifluoroacetate salt
Properties
Computed structural propertiesFilling in
- XLogP
- -5.5
- Topological polar surface area
- 453 Ų
- Hydrogen bond donors
- 14
- Hydrogen bond acceptors
- 13
- Rotatable bonds
- 31
- Heavy atoms
- 69
- Formal charge
- 0
- Complexity
- 1,790
Physicochemical properties
- Density
- 1.44 · 1.44±0.1 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- pka
- 3.71 · 3.71±0.10(Predicted)
- Sequence
- 2 · Asp-Arg-Asn-Phe-Leu-Arg-Phe-NH2
Chemistry & industry
Applications
UsesNeuropeptide DF2 is a DRNFLRFamide neuropeptide orignally isolated from crayfish. which enhances transmitter release and stimulates the amplitude of excitatory post-synaptic potentials (EPSP) through the calcium/calmodulin-dependent protein kinase[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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