Boldenone
Basic information
- CAS
846-48-0- Standard SMILES
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@@H]2O- InChIKey
RSIHSRDYCUFFLA-DYKIIFRCSA-N- Molecular formula
- C19H26O2
- Average molar mass
- 286.4 g/mol
- Monoisotopic mass
- 286.19328007
Overview
Boldenone is an 3-oxo-1,4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been developed for veterinary use. It is a 17beta-hydroxy steroid, an anabolic androgenic steroid and a 3-oxo-Delta(1),Delta(4)-steroid.
Names & identifiers
- Preferred name
- Boldenone
- IUPAC
- (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
- English name
- Boldenone
- Molecular formula
- C19H26O2
- Molecular weight
- 286.41
Names & synonyms
BoldenoneDehydrotestosterone846-48-017beta-Boldenone1,2-Didehydrotestosterone1,2-Dehydrotestosteronedelta1-Testosterone17beta-Hydroxyandrosta-1,4-dien-3-oneBoldenonumBoldenona1,4-Androstadien-17beta-ol-3-one17beta-Hydroxyandrosta-1,4-diene-3-one
Show more names
BoldBOLDENONBOLDENONE UNDECILINATEBoldenoe17-BoldenoneBoldenonebaseBoldenone (eq)
5H7I2IP58XCHEBI:34584DTXSID208942011,4-androstadiene-17-beta-ol-3-oneRefChem:569797DTXCID201324247212-686-01-Dehydrotestosterone
Database identifiers
- CAS
846-48-0- PubChem CID
- 13308
- DTXSID
DTXSID20894201- ChEMBL
CHEMBL209073- ChEBI
CHEBI:34584
Properties
Computed structural properties
- XLogP
- 3.5
- Topological polar surface area
- 37.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 546
Experimental & physicochemical properties
Drugs
DEA NFLIS-Drug Category -> Steroids
DEA Schedule III Controlled Substance -> Anabolic steroids
Pharmaceuticals -> Listed in ZINC15
Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds
LipidsLipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C19 steroids (androgens) and derivatives [ST0202]
SpringerMaterials PropertiesChemical shift
Animal DrugsPharmaceuticals -> Animal Drugs -> Approved in Taiwan
Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section171.76 Ų [M+H]+
Physicochemical properties
- Melting point
- 164 · 164-166°C
- alpha
- 25 · D25 +25° (in chloroform)
- Boiling point
- 368.77 °C · 368.77°C (rough estimate)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (14.3%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P260, P263, P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P351+P338, P318, P321, P330, P332+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 14 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
DEA schedule III controlled substance
REACH registered substance: Boldenone (EC: 212-686-0)
Other Safety InformationIMAP assessments - Androsta-1,4-dien-3-one, 17-hydroxy-, (17.beta.)-: Environment tier I assessment
Hazard Classes and CategoriesSkin Irrit. 2 (14.3%)
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- WGK 3
- rtecs
- BV7994400
- hs_code
- 29372900
- risk_code
- 11-20/21/22-36
- Signal word
- Danger
- Symbol(GHS)
- GHS08
- hazard_code
- F,Xn
- safety_code
- 16-36/37
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Chemistry & industry
Pharmacology
Pharmacodynamics
Boldenone has primarily anabolic activity with low androgenic potency. The drug is commonly used in doping within bodybuilding, even though this use is illegal. If intended to assist in bodybuilding, the drug is taken as part of a steroid stack of other anabolic steroids, usually with a potent androgen like testosterone as the 'base' of the stack. Boldenone is an androgen that differs from 17b-testosterone (17b-T) by only one double bond at the 1-position, and the removal of the methyl group protecting the 17-OH group allows it to be orally active.
Mechanism of ActionBoldenone is a steroid hormone which has androgenic activity. Androgens bind to the androgen receptor, which regulates gene transcription.
Biological Half-Life14 days
MeSH Pharmacological ClassificationThese compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power.
Uses & manufacturing
Use ClassificationPharmaceuticals -> Animal Drugs -> Approved in Taiwan
Applications
DescriptionBoldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects.
DescriptionBoldenone (Item No. 15432) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including boldenone, have been used to enhance physical performance in athletes. Boldenone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.
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Compound notes
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