Basic information
- CAS
2225940-46-3- Standard SMILES
O=C(O)CCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O- InChIKey
HIZAHNGGMCSUEV-UHFFFAOYSA-N- Molecular formula
- C16H15N3O6
- Average molar mass
- 345.31 g/mol
- Monoisotopic mass
- 345.09608521
Names & identifiers
- Preferred name
- Pomalidomide-C2-acid
- IUPAC
- 3-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]propanoic acid
- English name
- β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
- Molecular formula
- C16H15N3O6
- Molecular weight
- 345.31
Names & synonyms
2225940-46-3Pomalidomide-C2-acid3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propanoic acidMFCD32898771N-[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]-b-alanine3-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]propanoic acid3-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}propanoic acidPomalidomide-C2-COOH3-[[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]amino]propanoic Acid3-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]propanoic acidorb1303325orb1303338
Show more names
Poma-C2-COOHThalidomide-NH-C2-COOHThalidomide-4-NH-C2-COOHPomalidomideC2acid,Pomalidomide-C-2-acid,Pomalidomide C2 acidN-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-β-alanineβ-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
SCHEMBL20242499C16H15N3O6EBC-70116AKOS040757702NCGC00887234-02AC-37838BP-40549SY378960
Properties
Computed structural properties
- XLogP
- 0.4
- Topological polar surface area
- 133 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 5
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 633
Physicochemical properties
- Boiling point
- 708.5 · 708.5±60.0 °C(Predicted)
- Density
- 1.578 · 1.578±0.06 g/cm3(Predicted)
- storage temp.
- 2 · Storage temp. 2-8°C
- form
- Solid
- pka
- 4.42 · 4.42±0.10(Predicted)
- color
- Off-white to yellow
- Symbol(GHS)
- 8 · GHS08
- Signal word
- Warning
- Hazard statements
- 361 · H361
- Precautionary statements
- 501 · P501-P202-P201-P280-P308+P313-P405
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS08
- Hazard statements
- H361
- Precautionary statements
- P501-P202-P201-P280-P308+P313-P405
Chemistry & industry
Applications
UsesPomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Suppliers41 total
南京优氟医药科技有限公司025-86755008 17751752005 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
山东大有药物研发有限公司[email protected] 15165037910 · [email protected]
韶远科技（上海）有限公司4000665055 · [email protected]
大赛璐药物手性技术（上海）有限公司021-50460086-9 15921403865 · [email protected]
无锡捷化医药科技有限公司0510-83588313-811 18800520310 · [email protected]
泰州市众致生物科技有限公司[email protected] 15066129350 · [email protected]
上海敏寒医药科技有限公司17612188245 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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