2-Chloro-5-fluoro-4-methoxypyrimidine

HCID 13530704
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Basic information

CAS
37554-70-4
Standard SMILES
COc1nc(Cl)ncc1F
InChIKey
HLVJKADQILYNGE-UHFFFAOYSA-N
Molecular formula
C5H4ClFN2O
Average molar mass
162.55 g/mol
Monoisotopic mass
161.9996186

Names & identifiers

Preferred name
2-Chloro-5-fluoro-4-methoxypyrimidine
IUPAC
2-chloro-5-fluoro-4-methoxypyrimidine
English name
2-chloro-5-fluoro-4-methoxypyrimidine
Molecular formula
C5H4ClFN2O
Molecular weight
162.55

Names & synonyms

2-CHLORO-5-FLUORO-4-METHOXYPYRIMIDINE37554-70-4DTXSID70543075RefChem:258931DTXCID90493861641-268-42-chloro-5-fluoro-4-methoxy-pyrimidineMFCD07440062Pyrimidine, 2-chloro-5-fluoro-4-methoxy-SCHEMBL1997439HLVJKADQILYNGE-UHFFFAOYSA-NALBB-018209
Show more names
2-Chloro-5-fluoro-4-methoxy-1,3-diazine
SBB0876492-chloro-4-methoxy-5-fluoropyrimidineAKOS002666052GS-5550SB57295SY083854CS-0045717F313136

Database identifiers

CAS
37554-70-4
PubChem CID
13530704
DTXSID
DTXSID70543075
EC Number
641-268-4

Properties

Computed structural properties

XLogP
1.6
Topological polar surface area
35 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
4
Rotatable bonds
1
Heavy atoms
10

Physicochemical properties

Boiling point
280.9 · 280.9±20.0 °C(Predicted)
Density
1.4 · 1.400±0.06 g/cm3(Predicted)
storage temp.
2 · under inert gas (nitrogen or Argon) at 2-8°C
form
low melting solid
pka
-1.05 · -1.05±0.29(Predicted)
Appearance
White to off-white Solid

Safety & regulation

Safety data

wgk
3
hs_code
2933599590
risk_code
22-41
Signal word
Danger
Symbol(GHS)
GHS05,GHS07
hazard_code
Xn

Chemistry & industry

Applications

Uses2-Chloro-5-fluoro-4-methoxypyrimidine can be used as therapeutic sGC (soluble guanylate cyclase) stimulators.

Suppliers48 total

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
南京翔睿科技有限公司021-021-00000000 15715199582
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海腾准生物科技有限公司19821570922 · [email protected]
Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]

Related reactions

11 records
New reaction record

Compound notes

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