Basic information
- CAS
48144-44-1- Standard SMILES
NC(N)=NC(N)=Nc1cccc(Cl)c1- InChIKey
DIHXJZHAIHGSAW-UHFFFAOYSA-N- Molecular formula
- C8H10ClN5
- Average molar mass
- 211.65 g/mol
- Monoisotopic mass
- 211.062473
Overview
M-Chlorophenylbiguanide is a member of biguanides and a member of monochlorobenzenes.
Names & identifiers
- Preferred name
- N-(3-Chlorophenyl)imidodicarbonimidic diamide
- IUPAC
- 2-(3-chlorophenyl)-1-(diaminomethylidene)guanidine
- English name
- 1-(3-chlorophenyl)biguanide
- Molecular formula
- C8H10ClN5
- Molecular weight
- 211.65
Names & synonyms
1-(3-Chlorophenyl)biguanide48144-44-11-(m-Chlorophenyl)biguanideN-(3-Chlorophenyl)imidodicarbonimidic diamide910A4X901VDTXSID70197436RefChem:926774DTXCID80119927m-ChlorophenylbiguanidemCPBG2-(3-chlorophenyl)-1-(diaminomethylidene)guanidineN-(3-chlorophenyl)-N'-(diaminomethylene)guanidine
Show more names
meta-chlorphenylbiguanideImidodicarbonimidic diamide, N-(3-chlorophenyl)-1-carbamimidamido-N-(3-chlorophenyl)methanimidamideCHEMBL13790MFCD05854288N-(3-Chlorophenyl)triimidodicarbonic diamidem-CPBG hydrochloride2-(3-chlorophenyl)-1-(diaminomethylene)guanidine
Database identifiers
- CAS
48144-44-1- PubChem CID
- 1354
- DTXSID
DTXSID70197436- ChEMBL
CHEMBL13790- ChEBI
CHEBI:32347- UNII
- 910A4X901V
- Nikkaji
- J341.557K
Properties
Computed structural properties
- XLogP
- 0.5
- Topological polar surface area
- 103 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 2
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 246
Physicochemical properties
- FDA UNII
- 910 A4X901V · 910A4X901V
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationEndogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.
Applications
Usesm-Chlorophenylbiguanide (mCPBG) is a potent high-affinity agonist of the 5-HT3 receptor, exhibiting an inhibitory effect on long-term potentiation (LTP) in the mossy fiber-CA3 system. mCPBG attenuates the magnitude of LTP at concentrations of 0.3-1 microM, demonstrating its role in modulating synaptic plasticity. Additionally, the impact of mCPBG on LTP is reversible by the GABAA receptor antagonist bicuculline, indicating a connection between its action and GABAergic neurotransmission.
Suppliers3 total
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Additional notes
DefinitionChEBI: M-Chlorophenylbiguanide is a member of monochlorobenzenes and a member of biguanides.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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