6-hydroxy-1H-indazole

Uses6-Hydroxyinazole is a light brown powder and an important pharmaceutical intermediate used to construct the core of active drug molecules. It has broad application prospects in the synthesis and screening of small molecule chemical drugs. 6-Hydroxyinazole has neuroprotective effects. Indazole and its derivatives possess various biological activities, such as anti-inflammatory, antitumor, antioxidant, hypoglycemic, anti-HIV, anti-tuberculosis, antiplatelet, and 5-HT3 receptor antagonism. In addition, indazole derivatives are widely used in herbicides and dyes. Indazole was originally defined as a "pyrazole-ringed benzene ring," belonging to the azole family. It contains only three elements: carbon, hydrogen, and oxygen, and is an aromatic heterocycle containing 10 electrons. Theoretically, depending on whether there are hydrogen atoms on the two nitrogen atoms, indazole exists in two tautomeric forms: 1H-indazole and 2H-indazole. When there are no substituents on the indazole, it mainly exists in the 1H-indazole form.