Basic information
- CAS
823178-43-4- Standard SMILES
Cl.O.O=C1CN2Cc3c(ccc(Cl)c3Cl)N=C2N1- InChIKey
YLFXXKJQBOJJIX-UHFFFAOYSA-N- Molecular formula
- C10H10Cl3N3O2
- Average molar mass
- 310.6 g/mol
Overview
See also: Anagrelide (annotation moved to).
Names & identifiers
- Preferred name
- Anagrelide Hydrochloride Hydrate
- IUPAC
- 6,7-dichloro-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one;hydrate;hydrochloride
- English name
- ANAGRELIDE HCL MONOHYDRATE
- Molecular formula
- C10H7Cl2N3O.ClH.H2O
- Molecular weight
- 310.5643
Names & synonyms
Anagrelide hydrochloride monohydrate823178-43-4UNII-YTM763Y5C8Agrylin (TN)AgrylinAnagrelide hydrochloride hydrateAnagrelide hydrochloride hydrate (JAN)ANAGRELIDE HYDROCHLORIDE HYDRATE [JAN]ANAGRELIDE HYDROCHLORIDE MONOHYDRATE [MI]ANAGRELIDE HYDROCHLORIDE MONOHYDRATE [WHO-DD]RefChem:199580Anagrelide HCl monohydrate
Show more names
Anagrelide impurity 36Anagrelide Hydrochloride (100 mg)Anagrelide Hydrochloride (1034738)
6,7-dichloro-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one;hydrate;hydrochlorideBL4162AXagrid6,7-Dichloro-1,5-dihydroimidazo(2,1-b)quinazolin-2(3H)-one monohydrochloride monohydrateAnagrelide (hydrochloride monohydrate)6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one Monohydrochloride MonohydrateSCHEMBL729172orb1982131
Database identifiers
- CAS
823178-43-4- PubChem CID
- 135565321
- UNII
- YTM763Y5C8
- EC Number
- 805-322-2
Properties
Computed structural properties
- Topological polar surface area
- 45.7 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 360
Experimental & physicochemical properties
Human DrugsBreast Feeding; Lactation; Fibrinolytic Agents; Platelet Aggregation Inhibitors
Physicochemical properties
- storage temp.
- 2 · 2-8°C
- Major Application
- pharmaceutical (small molecule)
- InChI
- 1S/C10H7Cl2N3O.ClH.H2O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;;/h1-2H,3-4H2,(H,13,14,16);1H;1H2
- InChIKey
- YLFXXKJQBOJJIX-UHFFFAOYSA-N
- FDA UNII
- 763 Y5C8 · YTM763Y5C8
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 24 · NA.24
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
- WGK Germany
- 3 · WGK 3
- HS Code
- 2933595960 · 2933595960
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral]
P260, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (66.7%)
Toxicology
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation
Safety data
- wgk
- WGK 3
- hs_code
- 2933595960
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Applications
UsesAnagrelide Hydrochloride Monohydrate is an anhydrous salt of Anagrelide. Anagrelide is a platelet-lowering drug that inhibits bone marrow megakaryocytopoiesis.
Suppliers11 total
天津始加生物医药科技有限公司15022261580 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
深圳市星跃生物科技有限公司18124513697; 18124513697 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
上海修时生物医药有限公司15002184385 15021598081 15002184385 · [email protected]
湖北扬信医药科技有限公司15374522761 · [email protected]
华阴市赛普生物科技有限公司13892502238 · [email protected]
医恩医疗系统研发(上海)有限公司021-58958002 18930822973 · [email protected]
广州市桐晖药业有限公司020-66392521-118 18922260391 · [email protected]
AFINE CHEMICALS LIMITED+86-571-85134551 +86-18958018566 · [email protected]
上海安毕达生物科技有限公司021-61629020 18201956406 · [email protected]
Related reactions
1 records
Compound notes
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