Ridostin
Basic information
- CAS
112279-02-4- Standard SMILES
Nc1ccn(C2OC(COP(=O)(O)O)C(OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3OP(=O)(O)OCC3OC(n4ccc(=O)[nH]c4=O)C(O)C3OP(=O)(O)OCC3OC(n4cnc5c(=O)[nH]c(N)nc54)C(O)C3O)C2O)c(=O)n1.Nc1ccn(C2OC(COP(=O)(O)OC3C(COP(=O)(O)OC4C(COP(=O)(O)OC5C(CO)OC(n6cnc7c(=O)[nH]c(N)nc76)C5O)OC(n5ccc(=O)[nH]c5=O)C4O)OC(n4cnc5c(N)ncnc54)C3O)C(O)C2O)c(=O)n1- InChIKey
OIMSZUDJRCJRFX-UHFFFAOYSA-N- Molecular formula
- C76H97N30O55P7
- Average molar mass
- 2,527.6 g/mol
- Monoisotopic mass
- 2,526.3878863
Overview
Russian drug; inhibits HIV-1 replication in MT-4 & CEM cultures
Names & identifiers
- Preferred name
- Ridostin
- IUPAC
- [3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-4-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate;[5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [3-[[3-[[5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-4-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxyoxolan-2-yl]methyl hydrogen phosphate
- English name
- ridostin
- Molecular formula
- C76H97N30O55P7
- Molecular weight
- 2527.567707
Names & synonyms
Ridostin112279-02-4RefChem:179420SCHEMBL29409492DTXSID501365317
Database identifiers
- CAS
112279-02-4- PubChem CID
- 136170993
- DTXSID
DTXSID501365317
Properties
Computed structural properties
- Topological polar surface area
- 1,220 Ų
- Hydrogen bond donors
- 29
- Hydrogen bond acceptors
- 67
- Rotatable bonds
- 42
- Heavy atoms
- 168
- Formal charge
- 0
- Complexity
- 5,680
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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