4-(Trifluoromethyl)phenylhydrazine (HCID 136200)

Names & identifiers

Preferred name: 4-(Trifluoromethyl)phenylhydrazine
IUPAC: [4-(trifluoromethyl)phenyl]hydrazine
English name: 4-(Trifluoromethyl)phenylhydrazine
Molecular formula: C7H7F3N2
Molecular weight: 176.14

Names & synonyms

4-(Trifluoromethyl)phenylhydrazine368-90-14-trifluoromethylphenylhydrazineDTXSID40190277RefChem:517171DTXCID50112768609-305-9(4-(Trifluoromethyl)phenyl)hydrazine[4-(trifluoromethyl)phenyl]hydrazine4-(trifluoromethyl)phenyl hydrazineMFCD00042508p-Trifluoromethylphenylhydrazine

Show more names

BUTTPARK 44\57-164-(Trifluromethyl)phenylhydrà,à,à-trifluoro-p-tolylhydrazineP-(TRIFLUOROMETHYL)PHENYLHYDRAZINE4-(Trifluoromethyl)phenylhydrazine97%4-(Trifluoromethyl)phenylhydrazine,96%1-[4-(trifluoromethyl)phenyl]hydrazine4-(Trifluoromethyl)phenylhydrazine,95%4-(Trifluoromethyl)phenylhydrazine 97%

Hydrazine, [4-(trifluoromethyl)phenyl]-4-trifluoromethyl-phenylhydrazine(4-trifluoromethyl-phenyl)-hydrazineSTK500360GS-3179AC-149144-Hydrazinobenzotrifluoride4-(Trifluoromethyl)-phenylhydrazine

Database identifiers

CAS: 368-90-1
PubChem CID: 136200
DTXSID: DTXSID40190277
EC Number: 609-305-9
Nikkaji: J308.981I

Properties

Computed structural properties

XLogP: 2.4
Topological polar surface area: 38.1 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 5
Rotatable bonds: 1
Heavy atoms: 12
Formal charge: 0
Complexity: 138

Physicochemical properties

Melting point: 63 · 63-65 °C (lit.)
Boiling point: 118 · 118-122 °C/17 mmHg (lit.)
Density: 1.2773 · 1.2773 (estimate)
Flash point: 119 · 119-121°C/17mm
storage temp.: 2 · 2-8°C
pka: 4.49 · 4.49±0.20(Predicted)
form: Powder
color: Yellow to brown
Water Solubility: Insoluble in water.
BRN: 743759 · 743759
InChI: 1S/C7H7F3N2/c8-7(9,10)5-1-3-6(12-11)4-2-5/h1-4,12H,11H2
InChIKey: DBNLGTYGKCMLLR-UHFFFAOYSA-N
SMILES: NNc1ccc(cc1)C(F)(F)F
CAS DataBase Reference: 368 · 368-90-1(CAS DataBase Reference)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H319-H335
Precautionary statements: 261 · P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs: Respiratory system
PPE: 95 · dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes: Xi,T,Xn
Risk Statements: 36 · 36/37/38-20/21/22
Safety Statements: 26 · 26-36-24/25
RIDADR: 2811 · 2811
WGK Germany: 3 · 3
Hazard Note: Irritant
HazardClass: IRRITANT, TOXIC
PackingGroup: III
HS Code: 29280000 · 29280000
Storage Class: 11 · 11 - Combustible Solids
Hazard Classifications: 2 Skin · Eye Irrit. 2Skin Irrit. 2STOT SE 3

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (14.9%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (14.9%)

Safety data

PPE: dust mask type N95 (US), Eyeshields, Gloves
wgk: 3
ridadr: 2811
hs_code: 29280000
risk_code: 36/37/38-20/21/22
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi,T,Xn
hazard_note: Irritant
safety_code: 26-36-24/25
hazard_class: IRRITANT, TOXIC
Storage Class: 11 - Combustible Solids
packing_group: III
target organs: Respiratory system
Hazard statements: H315-H319-H335
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Chemistry & industry

Applications

Uses4-(Trifluoromethyl)phenylhydrazine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

General Description4-(Trifluoromethyl)phenylhydrazine participates as phenylhydrazine-based reductant containing fluorine atoms in the one-step reduction and functionalization of graphene oxide.