Basic information
- CAS
60221-37-6- Standard SMILES
OCCOCCOCCOC1CCCCO1- InChIKey
KUBUREHZQPDYHT-UHFFFAOYSA-N- Molecular formula
- C11H22O5
- Average molar mass
- 234.29 g/mol
- Monoisotopic mass
- 234.1467238
Names & identifiers
- Preferred name
- Thp-peg3-OH
- IUPAC
- 2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethanol
- English name
- THP-PEG4
- Molecular formula
- C11H22O5
- Molecular weight
- 234.29
Names & synonyms
60221-37-6THP-PEG3-OHTHP-PEG42-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-olMFCD28976687Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]-2-{2-[2-(oxan-2-yloxy)ethoxy]ethoxy}ethan-1-olMS-208702-(2-{2-[(Oxan-2-yl)oxy]ethoxy}ethoxy)ethan-1-ol2-{2-[2-(Tetrahydro-pyran-2-yloxy)-ethoxy]-ethoxy}-ethanol2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethanolSCHEMBL578640
Show more names
HO-PEG3-THPOH-PEG3-THP8-(1H-tetrahydropyran-2-yloxy)-3n63-dioxaoctan-1-ol2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]tetrahydro-2H-pyran2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethanol
orb1909261DTXSID405470402-{2-[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]ethoxy}ethanolAKOS037654852BP-22825DA-78440SY422285HY-130216
Database identifiers
- CAS
60221-37-6- PubChem CID
- 13699403
- DTXSID
DTXSID40547040- Nikkaji
- J761.158G
Properties
Computed structural properties
- XLogP
- 0
- Topological polar surface area
- 57.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 9
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 153
Physicochemical properties
- Boiling point
- 270 °C · 270 °C
- Density
- 1.09 · 1.09±0.1 g/cm3(Predicted)
- storage temp.
- 2 · Storage temp. 2-8°C
- form
- Liquid
- pka
- 14.36 · 14.36±0.10(Predicted)
- color
- Colorless to light yellow
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 280 · P280-P302+P352-P305+P351+P338
- HS Code
- 2942000090 · 2942000090
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- hs_code
- 2942000090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P280-P302+P352-P305+P351+P338
Chemistry & industry
Applications
DescriptionTHP-PEG4 is PEG linker containing a THP protecting group and a terminal hydroxyl. THP is an acid labile, alcohol protecting group. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG chain increases the water solubility of the compound in aqueous environments. The water solubility properties of the PEG linker are enhanced with longer PEG chains.
UsesTHP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Upstream & downstream products
Downstream products
Suppliers38 total
上海康恩博医药科技有限公司（科小研试剂）400-1388-521 17510465506 · [email protected]
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
郑州汇聚化工有限公司13393710386 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]
常州科化生物科技有限公司0519-68985668 13685222090 · [email protected]
吉林中科研伸科技有限公司18143011203 · [email protected]
吉林中科研伸科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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