Basic information
- CAS
965-52-6- Standard SMILES
O=C(NN=Cc1ccc([N+](=O)[O-])o1)c1ccc(O)cc1- InChIKey
YCWSUKQGVSGXJO-UHFFFAOYSA-N- Molecular formula
- C12H9N3O5
- Average molar mass
- 275.22 g/mol
- Monoisotopic mass
- 275.0542204
Names & identifiers
- Preferred name
- Akabar
- IUPAC
- 4-hydroxy-N-[(5-nitrofuran-2-yl)methylideneamino]benzamide
- English name
- Nifuroxazide
- Molecular formula
- C12H9N3O5
- Molecular weight
- 275.22
Names & synonyms
Benzoic acid, 4-hydroxy-, [(5-nitro-2-furanyl)methylene]hydrazideAkabarSR-01000721893Prestwick0_000555Prestwick1_000555CBMicro_0146854-hydroxy-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazideSCHEMBL543480SPBio_002550CHEMBL1309180HMS2230L10HMS3372F20
Show more names
(nitro-5’furfurylidene-2’)hydroxy-4benzhydrazideAdral27-109RCNifuzideRC 30-109diarlidandicoferinercefurolercefurylr.c.27-109
HMS3652F07s4182AKOS025117034DB-057635N1181NS00007819SR-01000721893-2SR-01000721893-3
Database identifiers
- CAS
965-52-6- PubChem CID
- 13764
- DTXSID
DTXSID4045343- ChEMBL
CHEMBL1309180
Properties
Computed structural properties
- XLogP
- 2.1
- Topological polar surface area
- 121 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 387
Experimental & physicochemical properties
Human DrugsPharmaceuticals
Endocrine DisruptorsPotential endocrine disrupting compound
Physicochemical properties
- Melting point
- 281 · 281-283°C
- Boiling point
- 418.17 °C · 418.17°C (rough estimate)
- Density
- 1.3877 · 1.3877 (rough estimate)
- refractive index
- 1.57 · 1.5700 (estimate)
- storage temp.
- 2 · Inert atmosphere,2-8°C
- solubility
- Practically insoluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
- pka
- 8.36 · 8.36±0.15(Predicted)
- form
- Solid
- color
- Yellow
- BRN
- 4264976 · 4264976
- Major Application
- clinical testing
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- rtecs
- DH2528300
- Toxicity
- LD50 intraperitoneal in mouse: 1gm/kg
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H312-H332
- Precautionary statements
- P280
Chemistry & industry
Pharmacology
ATC CodeA07AX03
Uses & manufacturing
Use ClassificationPharmaceuticals
Applications
UsesNifuroxazide is an intestinal antiseptic. Nifuroxazide, is still used as a veterinary drug illegally in some countries. SEE H829102 as a test for antibiotic in broiler chickens.
Upstream & downstream products
Upstream raw materials
Suppliers100 total
常州帝通化工有限公司+86-0519-88298848 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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