CAS 1002-67-1 1-Ethoxy-2-(2-methoxyethoxy)ethane (HCID 13847)

Names & identifiers

Preferred name: 1-Ethoxy-2-(2-methoxyethoxy)ethane
IUPAC: 1-(2-ethoxyethoxy)-2-methoxyethane
English name: Diethylene glycol ethyl methyl ether
Molecular formula: C7H16O3
Molecular weight: 148.2

Names & synonyms

1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE1002-67-1Diethylene glycol ethyl methyl etherEthane, 1-ethoxy-2-(2-methoxyethoxy)-diethylene glycol methyl ethyl ether1-(2-ethoxyethoxy)-2-methoxyethane2,5,8-TrioxadecaneMFCD01727263LF64ICW5Y32-Ethoxyethyl 2-methoxyethyl etherME2EINECS 213-690-5

Show more names

DEMEDEMEEDGMEEDiethylene Glycol Methyl AcetateDIETHYLENE GLYCOL METHYL ETHYL ETHE

Ether, 2-ethoxyethyl 2-methoxyethylUNII-LF64ICW5Y3BRN 1698464Ethylmethylether diethylenglykolu [Czech]Ethylmethylether diethylenglykolu1-(2-ethoxyethoxy)-2-methoxy-ethaneHISOLVE EDMEthane, 1-(2-ethoxyethoxy)-2-methoxy-

Database identifiers

CAS: 1002-67-1
PubChem CID: 13847
DTXSID: DTXSID80883636
UNII: LF64ICW5Y3
EC Number: 213-690-5
Nikkaji: J49.868H

Properties

Computed structural properties

XLogP: 0
Topological polar surface area: 27.7 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 3
Rotatable bonds: 7
Heavy atoms: 10
Formal charge: 0
Complexity: 56.8

Experimental & physicochemical properties

DrugsPharmaceuticals -> Listed in ZINC15

SpringerMaterials PropertiesDensity

Physical DescriptionLiquid

Physicochemical properties

Melting point: -72 °C · -72°C
Boiling point: 208.81 °C · 208.81°C (rough estimate)
Density: 1.01 · 1.0100 (rough estimate)
vapor pressure: 2.1 Pa · 2.1Pa at 25℃
refractive index: 1.408 · 1.4080-1.4120
Flash point: 82 °C · 82°C
storage temp.: 30 °C · Store below +30°C.
solubility: 76 g/L · 76 g/L
form: clear liquid
color: Colorless to Almost colorless
Water Solubility: 1000 g/L · 1000g/L at 20℃
InChI: InChI=1S/C7H16O3/c1-3-9-6-7-10-5-4-8-2/h3-7H2,1-2H3
InChIKey: CNJRPYFBORAQAU-UHFFFAOYSA-N
SMILES: C(OCC)COCCOC
LogP: -0.1 at · -0.1 at 20℃
CAS DataBase Reference: 1002 · 1002-67-1(CAS DataBase Reference)
FDA UNII: 64 ICW5Y3 · LF64ICW5Y3
EPA Substance Registry System: Diethylene glycol ethyl methyl ether (1002-67-1)
UNSPSC Code: 12352112 · 12352112
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02
Signal word: Warning
Hazard statements: 226 · H226
Precautionary statements: 210 · P210-P233-P240-P241+P242+P243-P280-P303+P361+P353-P403+P235-P501
RIDADR: 3271 · 3271
WGK Germany: 2 water · WGK 2 water endangering
RTECS: 9650000 · KN9650000
TSCA: TSCA listed
HS Code: 2909 · 2909 19 90
Storage Class: 10 · 10 - Combustible liquids
Toxicity: 50 orally · LD50 orally in Rabbit: 6000 mg/kg LD50 dermal Rabbit 6500 mg/kg
REACH Registrations: Active

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 82.9% (300 of 362) of all reports.

Warning

H319 (11.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 362 reports by companies from 6 notifications to the ECHA C&L Inventory.

Danger

Hazard information

Regulatory Information · 5 items

Chemical: Ethane, 1-ethoxy-2-(2-methoxyethoxy)-

Ethane, 1-ethoxy-2-(2-methoxyethoxy)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethane, 1-ethoxy-2-(2-methoxyethoxy)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 24-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/19407

1-Ethoxy-2-(2-methoxyethoxy)ethane: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 2 items

Eye Irrit. 2 (11.6%)

Flammable liquids - Category 4

Safety data

wgk: WGK 2 water endangering
tsca: TSCA listed
rtecs: KN9650000
ridadr: 3271
hs_code: 2909 19 90
Toxicity: LD50 orally in Rabbit: 6000 mg/kg LD50 dermal Rabbit 6500 mg/kg
Signal word: Warning
Symbol(GHS): GHS02
Storage Class: 10 - Combustible liquids
Hazard statements: H226
REACH Registrations: Active
Precautionary statements: P210-P233-P240-P241+P242+P243-P280-P303+P361+P353-P403+P235-P501

Chemistry & industry

Uses & manufacturing

U.S. Production2023: 700,000 - <850,000 lb

Consumer UsesSolvent

Industry UsesOther

General Manufacturing Information · 2 items

Printing and Related Support Activities

Ethane, 1-ethoxy-2-(2-methoxyethoxy)-: ACTIVE

Applications · 2 items

UsesDIETHYLENE GLYCOL ETHYL METHYL ETHER (cas# 1002-67-1) is a useful research chemical.

DescriptionDiethylene glycol ethyl methyl ether (DEGEME) is an aromatic hydrocarbon that has a carbonyl group. It is used in the production of polyurethane elastomers and as a solvent for nitrocellulose and other coatings. DEGEME has been detected in the environment, food, and cosmetics at low levels. The detection sensitivity of DEGEME is very high, making it useful for detecting other substances such as glycol ethers, fatty acids, aliphatic hydrocarbons, and cross-linking agents. Diethylene glycol ethyl methyl ether may be carcinogenic due to its reactive hydroxyl group and its ability to cross-link DNA.