Basic information
- CAS
17228-63-6- Standard SMILES
Cn1c(Cl)cccc1=O- InChIKey
WTMIJNWKTCXRBK-UHFFFAOYSA-N- Molecular formula
- C6H6ClNO
- Average molar mass
- 143.57 g/mol
- Monoisotopic mass
- 143.0137915
Names & identifiers
- Preferred name
- 6-Chloro-1-methylpyridin-2(1H)-one
- IUPAC
- 6-chloro-1-methylpyridin-2-one
- English name
- 6-Chloro-1-methyl-2(1H)pyridinone
- Molecular formula
- C6H6ClNO
- Molecular weight
- 143.57
Names & synonyms
6-Chloro-1-methylpyridin-2(1H)-one17228-63-66-chloro-1-methylpyridin-2-one6-Chloro-1-methyl-2(1H)pyridinone1-Methyl-6-chloro-pyrid-2-oneMFCD009557636-Chloro-1-methyl-1H-pyridin-2-one2(1H)-Pyridinone, 6-chloro-1-methyl-6-chloro-1-methyl-1,2-dihydropyridin-2-oneN-methyl-6-chloro-2-pyridoneSCHEMBL18505732-chloro-1-methyl-pyrid-6-one
Show more names
DTXSID401692466-chloro-1-methyl-pyridin-2-oneAKOS0159958946-Chloro-1-methyl-2(1H)-pyridinone #BS-11739FC142488SY115956CS-0213252
Database identifiers
- CAS
17228-63-6- PubChem CID
- 140201
- DTXSID
DTXSID40169246- EC Number
- 164-319-8
- Nikkaji
- J127.302G
Properties
Computed structural properties
- XLogP
- 1.2
- Topological polar surface area
- 20.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 9
- Formal charge
- 0
- Complexity
- 195
Physicochemical properties
- Boiling point
- 269.1 · 269.1±33.0 °C(Predicted)
- Density
- 1.29 · 1.29±0.1 g/cm3(Predicted)
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.98 · -0.98±0.62(Predicted)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319
- Precautionary statements
- 261 · P261-P305+P351+P338
- HS Code
- 2933399990 · 2933399990
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- hs_code
- 2933399990
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
Uses6-Chloro-1-methylpyridin-2(1H)-one is used in preparation of substituted pyrimidinones for inhibiting the activity of SHP2.
Upstream & downstream products
Upstream raw materials
Suppliers21 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
常州科化生物科技有限公司0519-68985668 13685222090 · [email protected]
南京圣亿来化工有限公司19951936396 · [email protected]
苏州亚衍医药科技有限公司17715136450 · [email protected]
上海安米克化学品有限公司微信 18019252918 18019252918 · [email protected]
苏州施亚生物科技有限公司86(512)5235 8471 17715136450 · [email protected]
泰州市众致生物科技有限公司[email protected] 15066129350 · [email protected]
合肥恩立医药科技有限公司
Related reactions
1 records
Compound notes
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