Basic information
- CAS
90955-43-4- Standard SMILES
Br.Oc1cc2c(cc1Cl)CCNCC2c1ccccc1- InChIKey
XSWVQBLZJAURQF-UHFFFAOYSA-N- Molecular formula
- C16H17BrClNO
- Average molar mass
- 354.7 g/mol
- Monoisotopic mass
- 353.01820394
Names & identifiers
- Preferred name
- Sch-24518
- IUPAC
- 8-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol;hydrobromide
- English name
- 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-phenyl-, hydrobrom ide
- Molecular formula
- C16H17BrClNO
- Molecular weight
- 354.67
Names & synonyms
90955-43-4Sch 24518Sch-24518SK&F 835098-Chloro-2,3,4,5-tetrahydro-5-phenyl-1H-3-benzazepin-7-olRefChem:107001SK&F-835098-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol;hydrobromideCHEMBL540857Skf-83509orb1699368DTXSID20920039
Show more names
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-phenyl-, hydrobrom ide
SKF 835091H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-phenyl-, hydrobromideAKOS04074944210-chloro-6-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-trien-9-ol hydrobromideCS-0034469T287078-Chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol--hydrogen bromide (1/1)
Database identifiers
- CAS
90955-43-4- PubChem CID
- 146265
- DTXSID
DTXSID20920039- ChEMBL
CHEMBL540857
Properties
Computed structural properties
- Topological polar surface area
- 32.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 292
Chemistry & industry
Applications
DescriptionSch 24518 is a D1 receptor antagonist.
UsesSKF 83509, a desmethyl analogue of SCH 23390 (HY-19545A), is a selective dopamine D1 antagonist with a Ki of 70.2 nM. SKF 83509 has no activity at dopamine D2 receptors[1].
Suppliers3 total
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…