Basic information
- CAS
1255-49-8- Standard SMILES
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2OC(=O)CCc1ccccc1- InChIKey
HHSXYDOROIURIP-FEZCWRLCSA-N- Molecular formula
- C28H36O3
- Average molar mass
- 420.6 g/mol
- Monoisotopic mass
- 420.26644501
Overview
Testosterone phenylpropionate is a steroid ester.
Names & identifiers
- Preferred name
- Testosterone phenylpropionate
- IUPAC
- [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] 3-phenylpropanoate
- English name
- Testosterone phenylpropionate
- Molecular formula
- C28H36O3
- Molecular weight
- 420.58
Names & synonyms
Testosterone phenylpropionate1255-49-8Testosterone 17-phenylpropionateDTXSID50487128GN84GWX51[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] 3-phenylpropanoate17beta-Hydroxyandrost-4-en-3-one 3-phenylpropionateNSC-26643DTXCID8028638TESTOSTERONE PHENYL PROPIONATE((8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-17-yl) 3-phenylpropanoateRefChem:188335
Show more names
Test phenylpropionateNphenTest PPTest nppTest phenStosteroneTest phenyTestosterone PhyenylTesto phenylpropionate
215-014-4RetandrolTestosterone phenpropionateTestosterone hydrocinnamateTestosterone, hydrocinnamateAndrost-4-en-3-one, 17-(1-oxo-3-phenylpropoxy)-, (17beta)-C28H36O3(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl 3-phenylpropanoate
Properties
Computed structural properties
- XLogP
- 5.8
- Topological polar surface area
- 43.4 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 31
- Formal charge
- 0
- Complexity
- 747
Experimental & physicochemical properties
DrugsPharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds
Human DrugsPharmaceuticals
Endocrine DisruptorsPotential endocrine disrupting compound
Physicochemical properties
- Melting point
- 116.5 °C · 116.5 °C
- Boiling point
- 497.74 °C · 497.74°C (rough estimate)
- Density
- 1.0043 · 1.0043 (rough estimate)
- refractive index
- 1.546 · 1.5460 (estimate)
- solubility
- 25 mg/mL; · DMF: 25 mg/mL; DMSO: 5 mg/mL; Ethanol: 15 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
- Water Solubility
- 2.25 mg/L · 2.25mg/L(25 ºC)
- InChIKey
- HHSXYDOROIURIP-FEZCWRLCSA-N
- SMILES
- [C@@]12(CC[C@]3(C)[C@H](CC[C@@]3([H])[C@@]1(CCC1=CC(=O)CC[C@]21C)[H])OC(=O)CCC1C=CC=CC=1)[H] |&1:0,3,5,8,10,19,r|
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (96.6%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P260, P261, P264, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P317, P318, P319, P321, P330, P362+P364, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 58 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationTestosterone phenyl propionate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Other Safety InformationIMAP assessments - Androst-4-en-3-one, 17-(1-oxo-3-phenylpropoxy)-, (17.beta.)-: Human health tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (96.6%)
Safety data
- wgk
- 3
- rtecs
- XA3105000
- risk_code
- 20/21/22-40
- Signal word
- Warning
- Symbol(GHS)
- GHS07,GHS08,GHS09
- hazard_code
- Xn
- safety_code
- 22-36
- Hazard statements
- H302-H351-H361-H410
- Precautionary statements
- P201-P273-P301+P312+P330-P308+P313
Chemistry & industry
Uses & manufacturing
Use ClassificationPharmaceuticals
Applications
DescriptionTestosterone phenylpropionate (BAN; TPP) (brand name Testolent), or testosterone phenpropionate, also known as testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester – specifically, the C17β phenylpropionate ester of testosterone – which was formerly marketed in Romania. It was first synthesized in 1951 and was first described in the literature by 1953. The medication was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren, as well as of Estandron Prolongatum, Lynandron Prolongatum, and Mixogen. TPP was previously available in Great Britain.
UsesTestosterone 17-Phenylpropionate, is one of the 17b-fatty acid esters of testosterone, that is increasingly misused by athletes in an attempt to improve sports performance, and thus can be used in doping control. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.
Upstream & downstream products
Upstream raw materials
Suppliers100 total
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
艾吉析科技（上海）有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…