Basic information
- CAS
1323-39-3- Standard SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(C)O- InChIKey
FKOKUHFZNIUSLW-UHFFFAOYSA-N- Molecular formula
- C21H42O3
- Average molar mass
- 342.6 g/mol
- Monoisotopic mass
- 342.3133952
Overview
2-Hydroxypropyl stearate is a fatty acid ester.
Names & identifiers
- Preferred name
- Propylene Glycol Monostearate
- IUPAC
- 2-hydroxypropyl octadecanoate
- English name
- PROPYLENE GLYCOL MONOSTEARATE
- Molecular formula
- C21H42O3
- Molecular weight
- 342.56
Names & synonyms
PROPYLENE GLYCOL MONOSTEARATE1323-39-3Cerasynt PAOctadecanoic acid, monoester with 1,2-propanediolFEMA No. 2942MZM1I680W0Propylene glycol palmitostearateFEMA NO. 4208NSC-4841RefChem:1097053F76354LMGRPROPYLENE GLYCOL MONOPALMITOSTEARATE
Show more names
Einecs 205-557-52-HydroxypropylstearatPropyleneglycol1-monostearate1,2-Propylene glycol 1-stearate1,2-Propylene glycol 1-octadecanoateOctadecanoicacid,2-hydroxypropylester
215-354-3617-037-92-Hydroxypropyl stearate2-hydroxypropyl octadecanoate142-75-6Propylene glycol stearateMonosteolProstearin
Database identifiers
- CAS
1323-39-3、142-75-6、8028-46-4- PubChem CID
- 14878
- DTXSID
DTXSID30872292- ChEMBL
CHEMBL1551666
Properties
Computed structural properties
- XLogP
- 8.3
- Topological polar surface area
- 46.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 19
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 266
Experimental & physicochemical properties
LipidsFatty Acyls [FA] -> Fatty esters [FA07] -> Short fatty esters [FA0710]
Cosmetics
Cosmetic ingredients (Propylene Glycol Stearate) -> CIR (Cosmetic Ingredient Review)
Opacifying; Emollient; Emulsifying
Food AdditivesEMULSIFIER OR EMULSIFIER SALT, FLAVORING AGENT OR ADJUVANT, STABILIZER OR THICKENER -> FDA Substance added to food
Solubility
insoluble in water
soluble in alcohol (in ethanol)
Melting Point50 °C
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description
Solid
white beads or flakes with a faint fatty odour
Physicochemical properties
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 86.7% (254 of 293) of all reports.
H413 (13.3%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
P273, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 293 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: Octadecanoic acid, 2-hydroxypropyl ester
Chemical: Octadecanoic acid, monoester with 1,2-propanediol
REACH registered substance: Stearic acid, monoester with propane-1,2-diol (EC: 215-354-3)
Propylene glycol monostearate: Does not have an individual approval but may be used under an appropriate group standard
Octadecanoic acid, 2-hydroxypropyl ester: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Octadecanoic acid, monoester with 1,2-propanediol: Human health tier I assessment
Hazard Classes and CategoriesAquatic Chronic 4 (13.3%)
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the following ingredients are safe in the present practices of use and concentration described in this safety assessment in cosmetics when formulated to be non-irritating...Propylene Glycol Stearate...
Safe for use in cosmetics, with qualifications
Safety data
Chemistry & industry
Pharmacology
Cellular LocationsExtracellular
Uses & manufacturing
UsesCIR ingredient: Propylene Glycol Stearate
Household ProductsInformation on 7 consumer products that contain Propylene glycol stearate in the following categories is provided:
Use Classification
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Flavoring Agents -> JECFA Flavorings Index
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Cosmetics -> Opacifying; Emollient; Emulsifying
General Manufacturing Information
Octadecanoic acid, 2-hydroxypropyl ester: INACTIVE
Octadecanoic acid, monoester with 1,2-propanediol: ACTIVE
Applications
Uses2-Hydroxypropyl stearate is an ester product.
Preparation methods
PreparationProduced commercially by catalytic transesterification between propylene glycol and a hydrogenated vegetable oil such as soybean oil.
Suppliers14 total
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
武汉绿景丰华生物科技有限公司19972070065 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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