Dichlorotetramine palladium(II)
Basic information
- CAS
15974-14-8- Standard SMILES
N.N.N.N.[Cl][Pd][Cl]- InChIKey
AQBOUNVXZQRXNP-UHFFFAOYSA-L- Molecular formula
- Cl2H12N4Pd
- Average molar mass
- 245.45 g/mol
- Monoisotopic mass
- 243.94738
Overview
Tetraammine palladium(II) chloride is a coordination complex of palladium. Palladium is a chemical element with the chemical symbol Pd and an atomic number of 46. It is found as a free metal alloyed with gold and other platinum group metals and in the rare minerals cooperite and polarite. (L794)
Names & identifiers
- Preferred name
- Dichlorotetramine palladium(II)
- IUPAC
- azane;dichloropalladium
Names & synonyms
15974-14-8Dichlorotetramine palladium(II)Tetramine dichloropalladium(II)RefChem:920084Tetraamminepalladium(II) dichlorideTetraamminepalladium(II) chlorideMFCD00064501Tetraamine palladiumTetraaminepalladouschloridePalladiumtetraamminedichlorideSCHEMBL526230tetraaminepalladium(ii) chloride
Show more names
Tetraamminepalladium(II)dichloridePalladium(II) tetraammine chloridePALLADIUM TETRAMMINEDICHLORIDEAKOS015853722CS-0083684Palladium(2+), tetraammine-, (SP-4-1)-tetraammine-,dichloride,(sp-4-1)-palladium(2++tetraammine-,dichloride,(SP-4-1)-Palladium(2+)
Database identifiers
- CAS
15974-14-8- PubChem CID
- 152124
Properties
Computed structural properties
- Topological polar surface area
- 4 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 0
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 2.8
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Toxicology
Treatment
EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
Health EffectsContact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798)
Toxicity Summary
Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798)
Signs and SymptomsSkin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Palladium may be absorbed through oral, dermal, and inhalation exposure. Once in the body it distributes to the kidney, liver, spleen, lymph nodes, adrenal gland, lung and bone. Palladium's ability to form complexes allows it the bind to amino acids, proteins, DNA, and other macromolecules. Palladium and its metabolites are excreted in the urine and faeces. (A21)
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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