Histidylphenylalanine
Basic information
- CAS
16874-81-0- Standard SMILES
N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O- InChIKey
XMAUFHMAAVTODF-STQMWFEESA-N- Molecular formula
- C15H18N4O3
- Average molar mass
- 302.33 g/mol
- Monoisotopic mass
- 302.13789044
Overview
His-Phe is a dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-phenylalanine. It is functionally related to a L-histidine and a L-phenylalanine.
Names & identifiers
- Preferred name
- Histidylphenylalanine
- IUPAC
- (2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoic acid
- English name
- H-His-Phe-OH
- Molecular formula
- C15H18N4O3
- Molecular weight
- 302.33
Names & synonyms
16874-81-0Histidylphenylalaninel-histidyl-l-phenylalanineHis-pheCHEBI:141438DTXSID70168606RefChem:146591DTXCID2091097PhenylalanylhistidineH-His-Phe-OHL-Phenylalanine, L-histidyl-HF dipeptide
Show more names
H-F DipeptideMFCD00037858(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoic acidCHEMBL1222393Histidine Phenylalanine dipeptideHistidyl-phenylalanineHistidinylphenylalanineN-histidyl-phenylalanine
Database identifiers
- CAS
16874-81-0- PubChem CID
- 152198
- DTXSID
DTXSID70168606- ChEMBL
CHEMBL1222393- ChEBI
CHEBI:141438- Nikkaji
- J346.808I
Properties
Computed structural properties
- XLogP
- -2.7
- Topological polar surface area
- 121 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 7
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 385
Experimental & physicochemical properties
LogP-2.3
Physical DescriptionSolid
Physicochemical properties
- Melting point
- 255 · 255-258 °C (decomp)
- Boiling point
- 693.4 · 693.4±55.0 °C(Predicted)
- Density
- 1.34 · 1.340±0.06 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- solubility
- Aqueous Acid (Slightly)
- form
- Solid
- pka
- 3.36 · 3.36±0.10(Predicted)
- color
- White to Off-White
- Sequence
- His-Phe
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
Chemistry & industry
Applications
UsesH-His-Phe-OH is adipeptide.
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionChEBI: His-Phe is a dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-phenylalanine. It is functionally related to a L-histidine and a L-phenylalanine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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