Basic information
- CAS
52899-09-9- Standard SMILES
CC(C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)O- InChIKey
AWJGUZSYVIVZGP-YUMQZZPRSA-N- Molecular formula
- C10H18N2O3
- Average molar mass
- 214.26 g/mol
- Monoisotopic mass
- 214.13174244
Overview
Pro-Val is a dipeptide formed from L-proline and L-valine residues. It has a role as a metabolite.
Names & identifiers
- Preferred name
- L-Prolyl-L-valine
- IUPAC
- (2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoic acid
- English name
- H-Pro-Val-OH
- Molecular formula
- C10H18N2O3
- Molecular weight
- 214.26
Names & synonyms
H-Pro-Val-OHL-Prolyl-L-valine(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoic acid(2S)-3-methyl-2-(((2S)-pyrrolidine-2-carbonyl)amino)butanoic acid(2S)-3-methyl-2-(((2S)-pyrrolidin-1-ium-2-carbonyl)amino)butanoate(2S)-3-methyl-2-[[(2S)-pyrrolidin-1-ium-2-carbonyl]amino]butanoateRefChem:797389109-172-252899-09-9Prolyl-Valine(2S)-3-methyl-2-{[(2S)-pyrrolidin-2-yl]formamido}butanoic acid(S)-3-Methyl-2-((S)-pyrrolidine-2-carboxamido)butanoic acid
Show more names
PRO-VALPROLINE-VALINEL-Propyl-L-valineL-Valine, L-prolyl-
l-pro l-valMFCD00037867L-Pro-L-Valstarbld0021942H-Pro-Val-OH, AldrichCPRCHEMBL59096SCHEMBL6401404CHEBI:74800
Database identifiers
- CAS
52899-09-9- PubChem CID
- 152307
- DTXSID
DTXSID801369075- ChEMBL
CHEMBL59096- ChEBI
CHEBI:74800- EC Number
- 109-172-2
- Nikkaji
- J149.646H
Properties
Computed structural properties
- XLogP
- -2.9
- Topological polar surface area
- 78.4 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 253
Physicochemical properties
- Melting point
- 221 °C · 221 °C
- Boiling point
- 451.1 · 451.1±45.0 °C(Predicted)
- Density
- 1.15 · 1.150±0.06 g/cm3(Predicted)
- storage temp.
- -15 °C · -15°C
- pka
- 3.54 · 3.54±0.10(Predicted)
- Sequence
- Pro-Val
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- risk_code
- 22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Applications
UsesH-Pro-Val-OH is a deprotonation dipeptide containing proline, which can catalyze the Michael addition reaction of acetone to trans-β-nitrostyrene. H-Pro Val OH can also serve as a substrate for fibroblast enzymes and prolinase, and has potential applications in biochemical analysis[1][2][3][4].
Upstream & downstream products
Upstream raw materials
Suppliers31 total
上海康恩博医药科技有限公司（科小研试剂）400-1388-521 17510465506 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
Shanghai Hanhong Scientific Co., Ltd.+undefined17612118332 · [email protected]
杭州专肽生物技术有限公司17342063383 · [email protected]
合肥合生生物科技有限公司0551-63802898 15395108618 · [email protected]
南京肽谷生物科技有限公司18115476705 · [email protected]
成都云希化工有限公司+86-17380623303 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
江苏艾康生物医药研发有限公司025-58859352 15955137747 · [email protected]
杭州肽佳生物科技有限公司0571-87213919 15967184799 · [email protected]
浙江杰坤生物科技有限公司15397062932 · [email protected]
南京源肽生物科技有限公司13357818155 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 18917919676 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
ANHUI BYERSEN BIOTECH CO. LTD+8617355064950 · [email protected]
吉尔生化(上海)有限公司21-61263452 13641803416 · [email protected]
Nextpeptide Inc+86-0571-81612335 +8613336028439 · [email protected]
南京肽研生物科技有限公司19961912513 19941518170 · [email protected]
Nanjing TGpeptide+86-13347807150 · [email protected]
合肥钼凯医药科技有限公司18001872185; 18001872185 · [email protected]
DONBOO AMINO ACID COMPANY13063595538 · [email protected]
绍兴市均宇生物科技有限公司0571-0571-88211921 19105816207 · [email protected]
浙江昂拓莱司生物技术有限公司0571-88760729 18072970094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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