Basic information
- CAS
124-28-7- Standard SMILES
CCCCCCCCCCCCCCCCCCN(C)C- InChIKey
NAPSCFZYZVSQHF-UHFFFAOYSA-N- Molecular formula
- C20H43N
- Average molar mass
- 297.6 g/mol
- Monoisotopic mass
- 297.33955038
Overview
N,n-dimethyl-1-octadecanamine appears as a clear yellow liquid with a fishlike odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals.
Names & identifiers
- Preferred name
- Dimethyloctadecylamine
- IUPAC
- N,N-dimethyloctadecan-1-amine
- English name
- N,N-Dimethyloctadecylamine
- Molecular formula
- C20H43N
- Molecular weight
- 297.56
Names & synonyms
124-28-7DymanthineN,N-DimethyloctadecylamineN,N-Dimethyl-n-octadecylamineDimethyloctadecylamineN,N-Dimethyl-1-octadecanamine1-Octadecanamine, N,N-dimethyl-OctadecyldimethylamineStearyldimethylamineOctadecylamine, N,N-dimethyl-N,N-DimethylstearylamineDimantina
Show more names
DimantineDimethyl stearamineDIMETHYL OCTADECYLAMINEDMA18DimantinOctadecyl Dimethyl Tertiary AmineN,N-Dimethyloctadecylamine hydrochloride
N,N-DimethyloctadecanamineKemamine 9902DArmeen DM 18DFarmin DM 80Adogen 342DDimethylstearamineDimethyl-N-octadecylamineDimantinum
Database identifiers
- CAS
124-28-7- PubChem CID
- 15365
- DTXSID
DTXSID4027026- ChEMBL
CHEMBL2110847
Properties
Computed structural properties
- XLogP
- 9.1
- Topological polar surface area
- 3.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 17
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 177
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
Cosmetics
Cosmetic ingredients (Dimethyl Stearamine) -> CIR (Cosmetic Ingredient Review)
Antistatic; Emulsifying; Hair conditioning
Personal care product -> emollient -> DIMLA: dimethyl lauryl amine
Endocrine DisruptorsPotential endocrine disrupting compound
Melting PointFREEZING POINT: 22.89 °C
Physical Description
N,n-dimethyl-1-octadecanamine appears as a clear yellow liquid with a fishlike odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals.
CBI; Liquid; Liquid; Other Solid
mp = 22.89 deg C; [ChemIDplus] Clear yellow liquid with a fishy odor; [CAMEO] Colorless to yellow liquid; Clear or slightly cloudy with a fishy odor; [MSDSonline]
Physicochemical properties
- Melting point
Safety & regulation
GHS classification
GHS Classification
Danger
H226 (53.9%): Flammable liquid and vapor [Warning Flammable liquids]
P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P370+P378, P391, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 833 reports by companies from 19 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
Hazard information
Regulatory Information
Chemical: 1-Octadecanamine, N,N-dimethyl-
1-Octadecanamine, N,N-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Octadecanamine, N,N-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 15-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14746
Dimethyl stearamine: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Tertiary aliphatic (C12-22) and fatty amines: Human health tier II assessment
DOT LabelCorrosive
Fire HazardsExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Health HazardsExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Hazards Summary
Emergency treatment: Irritants; [HSDB] Negative for mutagenicity in two strains of Salmonella typhimurium; [EPA HPVIS] Moderately irritating to skin and eyes; [RTECS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; [MSDSonline]
Chemistry & industry
Uses & manufacturing
Uses
CIR ingredient: Dimethyl Stearamine
Used as chemical intermediate and corrosion inhibitor for condensing systems; [HSDB]
CHEM INT FOR N,N-DIMETHYL-N-OCTADECYLAMINE OXIDE-AS MIXT
CHEM INT FOR BENZYL DIMETHYL OCTADECYL AMMONIUM CHLORIDE
FILMING AMINE CORROSION INHIBITOR FOR CONDENSING SYSTEMS
ANTHELMINTIC AGENT (HYDROCHLORIDE SALT)
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 1,000,000 - <2,500,000 lb
(1979) 5.62X10+8 GRAMS
(1981) PROBABLY GREATER THAN 9.08X10+6 GRAMS
Consumer UsesIntermediate
Industry UsesIntermediate
Methods of Manufacturing
...FROM OCTADECYLAMINE AND FORMALDEHYDE: RECK ET AL, J ORG CHEM 12: 517 (1947).
REACTION OF 1-OCTADECANOL WITH N,N-DIMETHYLAMINE; HYDROGENATION OF 9-OCTADECENENITRILE FOLLOWED BY REACTION WITH FORMALDEHYDE; REDUCTION OF N,N-DIMETHYL-N-OCTADECYLAMIDE
Formulations/PreparationsGS 1339, THELMESAN. /HYDROCHLORIDE/
Household ProductsInformation on 3 consumer products that contain Dimethyl Stearamine in the following categories is provided:
Use ClassificationCosmetics -> Antistatic; Emulsifying; Hair conditioning
General Manufacturing Information
Related reactions
13 records
Compound notes
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