Basic information
- CAS
1631-28-3- Standard SMILES
Cc1ccc(N2C(=O)C=CC2=O)cc1- InChIKey
KCFXNGDHQPMIAQ-UHFFFAOYSA-N- Molecular formula
- C11H9NO2
- Average molar mass
- 187.19 g/mol
- Monoisotopic mass
- 187.06332853
Names & identifiers
- Preferred name
- N-(4-Methylphenyl)maleimide
- IUPAC
- 1-(4-methylphenyl)pyrrole-2,5-dione
- English name
- 1-(4-Methylphenyl)-1H-pyrrole-2,5-dione
- Molecular formula
- C11H9NO2
- Molecular weight
- 187.19
Names & synonyms
1-(p-Tolyl)-1H-pyrrole-2,5-dioneN-(4-Methylphenyl)maleimideRefChem:827855654-866-51631-28-3p-Tolylmaleimide1-(4-Methylphenyl)-1H-pyrrole-2,5-dioneN-p-TolylmaleimideMALEIMIDE, N-p-TOLYL-1H-Pyrrole-2,5-dione, 1-(4-methylphenyl)-N-(p-Methylphenyl)maleimideMFCD00022581
Show more names
N-(P-TOLYL)MALEIMIDEAKOS B006714AKOS MSC-0013ASISCHEM S97813WLN: T5VNVJ BR D1n-p-tolyl-maleimidN-4-Tolylmaleimide
1-(4-methylphenyl)pyrrole-2,5-dionep TolylmaleimideN,p-TolylmaleimideNSC 13691IT 510LB7TXV3P6MN-(para-Tolyl)-maleimide1-(4-methylphenyl)-2,5-dihydro-1H-pyrrole-2,5-dione
Database identifiers
- CAS
1631-28-3、25989-85-9- PubChem CID
- 15399
- DTXSID
DTXSID10167512- ChEMBL
CHEMBL578795- UNII
- LB7TXV3P6M
- EC Number
- 654-866-5
- Nikkaji
- J38.922F
Properties
Computed structural properties
- XLogP
- 1.5
- Topological polar surface area
- 37.4 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 270
Physicochemical properties
- Melting point
- 149 · 149-150 °C
- Boiling point
- 333.2 · 333.2±21.0 °C(Predicted)
- Density
- 1.277 · 1.277±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- form
- Solid
- pka
- -0.29 · -0.29±0.20(Predicted)
- color
- Light yellow to yellow
- CAS DataBase Reference
- 1631 · 1631-28-3(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 7 TXV3P6M · LB7TXV3P6M
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319
- Precautionary statements
- 264 · P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- hazard_class
- IRRITANT
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Chemistry & industry
Applications
Usesp-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis[1].
Suppliers38 total
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
常州琬瑶生物科技有限公司051989185693 15312551983 · [email protected]
烟台盛凯伦生物制品有限公司13356901049 · [email protected]
河南阿尔法化工有限公司0371-55013243 15324716602 · [email protected]
烟台正信新材料科技有限公司13854547682 13854547682 · [email protected]
上海纳谦化学科技有限公司13598610367 0373-7129549 · [email protected]
Qingdao Dexin Chemical Co., Ltd+86-15553333686 · [email protected]
上海毕得医药科技股份有限公司
Related reactions
3 records
Compound notes
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