15-Aminopentadecanoic acid
Basic information
- CAS
17437-21-7- Standard SMILES
NCCCCCCCCCCCCCCC(=O)O- InChIKey
LDOUJNADNJHDOO-UHFFFAOYSA-N- Molecular formula
- C15H31NO2
- Average molar mass
- 257.41 g/mol
- Monoisotopic mass
- 257.23547923
Names & identifiers
- Preferred name
- 15-Aminopentadecanoic acid
- IUPAC
- 15-aminopentadecanoic acid
- English name
- 15-Aminopentadecanoic acid
- Molecular formula
- C15H31NO2
- Molecular weight
- 257.41
Names & synonyms
15-aminopentadecanoic acid17437-21-7RefChem:236604Pentadecanoic acid, 15-amino-MFCD3156716615-Amino-pentadecanoic acidSCHEMBL430130orb3029046DTXSID701311411AC4715AKOS037630178AS-78224
Show more names
BP-28233SY129787F803374T206077
Database identifiers
- CAS
17437-21-7- PubChem CID
- 15420362
- DTXSID
DTXSID701311411- Nikkaji
- J1.064.454B
Properties
Computed structural properties
- XLogP
- 1.1
- Topological polar surface area
- 63.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 14
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 183
Physicochemical properties
- Melting point
- 160 · 160-161 °C
- Boiling point
- 393 · 393.0±15.0 °C(Predicted)
- Density
- 0.937 · 0.937±0.06 g/cm3(Predicted)
- pka
- 4.78 · 4.78±0.10(Predicted)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
Description15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Uses15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Related reactions
0 records
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Compound notes
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