Basic information
- CAS
10593-78-9- Standard SMILES
c1ncc2c(n1)NCCN2- InChIKey
IDAICLIJTRXNER-UHFFFAOYSA-N- Molecular formula
- C6H8N4
- Average molar mass
- 136.15 g/mol
- Monoisotopic mass
- 136.07489627
Overview
5,6,7,8-tetrahydropteridine is a member of pteridines. It has a role as a cofactor and an Escherichia coli metabolite.
Names & identifiers
- Preferred name
- 5,6,7,8-Tetrahydropteridine
- IUPAC
- 5,6,7,8-tetrahydropteridine
- English name
- Pteridine, 5,6,7,8-tetrahydro- (6CI,7CI,8CI,9CI)
- Molecular formula
- C6H8N4
- Molecular weight
- 136.15
Names & synonyms
5,6,7,8-tetrahydropteridine10593-78-9tetrahydropteridineCHEBI:28889DTXSID00147429RefChem:101102DTXCID9069920Pteridine, 5,6,7,8-tetrahydro-Pteridine, 5,6,7,8-tetrahydro- (6CI,7CI,8CI,9CI)H4-biopterin343269-86-3SCHEMBL1448583
Show more names
5,6,7,8-tetrahydro-PteridineSCHEMBL20565496SCHEMBL30100337KAA59378AKOS006279616AT49771PTERIDINE, 1,5,6,7-TETRAHYDRO-DB-278021
Database identifiers
- CAS
10593-78-9- PubChem CID
- 156
- DTXSID
DTXSID00147429- ChEBI
CHEBI:28889- EC Number
- 196-846-4
- Nikkaji
- J113.487F
Properties
Computed structural properties
- XLogP
- 0.3
- Topological polar surface area
- 49.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 0
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 116
Experimental & physicochemical properties
Physical DescriptionSolid
Physicochemical properties
- Melting point
- 146 · 146-147 °C
- Boiling point
- 340.4 · 340.4±31.0 °C(Predicted)
- Density
- 1.186 · 1.186±0.06 g/cm3(Predicted)
- pka
- 6.6 · 6.60±0.10(Predicted)
Chemistry & industry
Pharmacology
Cellular LocationsCytoplasm
Applications
UsesWith stoichiometric amounts of the tetrahydropteridine, the initial rate of tyrosine formation is independent of both the sheep-liver enzyme and TPNH, a fact that makes it unlikely that either of these components is directly involved in the hydroxylation reaction.A putative cellular function of tetrahydropteridines was investigated in Dictyostelium discoideum Ax2 using a mutant disrupted in the gene encoding sepiapterin reductase.
Suppliers1 total
苏州诺行贸易有限公司0512-65816829 18662214788 · [email protected]
Additional notes
DefinitionChEBI: 5,6,7,8-tetrahydropteridine is a member of pteridines. It has a role as an Escherichia coli metabolite and a cofactor.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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