Disopyramide, (R)-
Completing data — refresh the page later to see the latest
Basic information
- CAS
74464-83-8- Standard SMILES
CC(C)N(CC[C@@](C(N)=O)(c1ccccc1)c1ccccn1)C(C)C- InChIKey
UVTNFZQICZKOEM-OAQYLSRUSA-N- Molecular formula
- C21H29N3O
- Average molar mass
- 339.5 g/mol
- Monoisotopic mass
- 339.23106256
Names & identifiers
- Preferred name
- Disopyramide, (R)-
- IUPAC
- (2R)-4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
- English name
- l-Disopyramide
- Molecular formula
- C21H29N3O
- Molecular weight
- 339.47446
Names & synonyms
(R)-DisopyramideDisopyramide, (R)-O14QWZ0EF774464-83-8DTXSID009046302-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (R)-RefChem:920495DTXCID001333751L-DISOPYRAMIDE(-)-DISOPYRAMIDEdisopiramide(R)-(-)-DISOPYRAMIDE
Show more names
(2R)-4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide(2R)-4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide[R,(-)]-4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide(αR)-α-[2-[Bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-, (R)-2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-, (αR)-
NCGC00016985-01DISOPYRAMIDE, L-Lopac-D-6035Lopac-D-7644UNII-O14QWZ0EF7BIDD:GT0523CHEMBL269362(-)-(R)-DISOPYRAMIDE
Database identifiers
- CAS
74464-83-8- PubChem CID
- 156294
- DTXSID
DTXSID00904630- ChEMBL
CHEMBL269362- UNII
- O14QWZ0EF7
- Nikkaji
- J413.004I
Properties
Computed structural propertiesFilling in
- XLogP
- 3.2
- Topological polar surface area
- 59.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 8
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 409
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physicochemical properties
- Melting point
- 83 · 83-85 °C
- Boiling point
- 505.2 · 505.2±50.0 °C(Predicted)
- Density
- 1.059 · 1.059±0.06 g/cm3(Predicted)
- pka
- 15.4 · 15.40±0.50(Predicted)
- FDA UNII
- 14 QWZ0EF7 · O14QWZ0EF7
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…