N-(Butoxymethyl)acrylamide

HCID 15817

Basic information

CAS
1852-16-0
Standard SMILES
C=CC(=O)NCOCCCC
InChIKey
UTSYWKJYFPPRAP-UHFFFAOYSA-N
Molecular formula
C8H15NO2
Average molar mass
157.21 g/mol
Monoisotopic mass
157.11027872

Names & identifiers

Preferred name
N-(Butoxymethyl)acrylamide
IUPAC
N-(butoxymethyl)prop-2-enamide
English name
N-(ISOBUTOXYMETHYL)ACRYLAMIDE
Molecular formula
C8H15NO2
Molecular weight
157.21

Names & synonyms

N-(BUTOXYMETHYL)ACRYLAMIDE1852-16-02-Propenamide, N-(butoxymethyl)-N-ButoxymethylacrylamideN-(Butoxymethyl)-2-propenamideN-ButoxymethylakrylamidAcrylamide, N-butoxymethyl-N-Butoxymethylakrylamid [Czech]HSDB 5859Acrylamide, N-(butoxymethyl)-DTXSID9027443EINECS 217-442-7
Show more names
IBMANBMN-(N-BUTOXYMETHYL)ACRYLAMIDENIBMAAlflutinib Impurity 1n-butoxymethyl-acrylamid(butoxymethyl)acrylamiden-(butoxymethyl)-2-propenamid
BRN 1906225CYLINK NBMAZ89G4O958ADTXCID907443N-(BUTOXYMETHYL)ACRYLAMIDE [HSDB]N-BUTOXYMETHYLAKRYLAMID (CZECH)NButoxymethylakrylamidNButoxymethylacrylamide

Database identifiers

CAS
1852-16-0
PubChem CID
15817
DTXSID
DTXSID9027443
ChEMBL
CHEMBL3187607
UNII
Z89G4O958A
EC Number
217-442-7
Nikkaji
J55.122H

Properties

Computed structural properties

XLogP
1.3
Topological polar surface area
38.3 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
2
Rotatable bonds
6
Heavy atoms
11

Experimental & physicochemical properties

Vapor Pressure0.00704 [mmHg]
Physical DescriptionCBI; Liquid

Physicochemical properties

Melting point
-9 · -9-6 °C
Boiling point
108 °C · 108 °C(lit.)
Density
0.96 g/mL · 0.96 g/mL at 25 °C(lit.)
vapor pressure
0.212 Pa · 0.212Pa at 20℃
refractive index
20 · n20/D 1.461(lit.)
Flash point
175 °F · 175 °F

Safety & regulation

GHS classification

GHS Classification · 6 items

Danger

H301 (27.3%): Toxic if swallowed [Danger Acute toxicity, oral];H302 (72.7%): Harmful if swallowed [Warning Acute toxicity, oral];H311 (28.1%): Toxic in contact with skin [Danger Acute toxicity, dermal];H312 (64%): Harmful in contact with skin [Warning Acute toxicity, dermal];H315 (40.3%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (40.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H331 (27.3%): Toxic if inhaled [Danger Acute toxicity, inhalation];H332 (15.8%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (40.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H350 (30.2%): May cause cancer [Danger Carcinogenicity];H361 (30.2%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

P203, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P317, P318, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 139 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 4 items

Chemical: 2-Propenamide, N-(butoxymethyl)-

2-Propenamide, N-(butoxymethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenamide, N-(butoxymethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 09-05-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/20691

2-Propenamide, N-(butoxymethyl)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards Summary · 1 item

Oral LD50 (rat) = 1030 mg/kg; [ChemIDplus] Hazardous polymerization may occur; A skin, eye, and respiratory tract irritant; Readily absorbed through skin; In high-dose animal studies, targets CNS, liver, lungs, eyes, kidneys, and male reproductive system; [MSDSonline]

Hazard Classes and Categories · 2 items

Acute Tox. 3 (27.3%);Acute Tox. 4 (72.7%);Acute Tox. 3 (28.1%);Acute Tox. 4 (64%);Skin Irrit. 2 (40.3%);Eye Irrit. 2 (40.3%);Acute Tox. 3 (27.3%);Acute Tox. 4 (15.8%);STOT SE 3 (40.3%);Carc. 1B (30.2%);Repr. 2 (30.2%)

Flammable liquids - Category 4;Acute toxicity (Oral) - Category 4;Acute toxicity (Dermal) - Category 3;Serious eye damage/eye irritation - Category 2B;Specific target organ toxicity - Single exposure - Category 1 (systemic toxicity)

Toxicology

Adverse EffectsNeurotoxin - Other CNS neurotoxin;Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Regulatory information

Regulatory Information · 4 items

Chemical: 2-Propenamide, N-(butoxymethyl)-

2-Propenamide, N-(butoxymethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenamide, N-(butoxymethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 09-05-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/20691

2-Propenamide, N-(butoxymethyl)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Safety data

wgk
3
tsca
TSCA listed
rtecs
AS3630000
ridadr
UN 2810 6.1/PG 3
hs_code
2924.19.8000
risk_code
21/22-63-36/37/38-23/24/25-46-45

Chemistry & industry

Uses & manufacturing

U.S. Production2023: 75,000 - <500,000 lb;2022: 75,000 - <500,000 lb;2021: 500,000 - <1,000,000 lb;2020: 75,000 - <500,000 lb
Consumer UsesAdhesion/cohesion promoter
Industry UsesAdhesion/cohesion promoter;Other
General Manufacturing Information · 2 items

Petrochemical Manufacturing;Plastics Material and Resin Manufacturing

2-Propenamide, N-(butoxymethyl)-: ACTIVE

Suppliers94 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]

Related reactions

1 records

Compound notes

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