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Basic information
- CAS
83643-88-3- Standard SMILES
Cc1o[nH]c(=O)c1C[C@H](N)C(=O)O- InChIKey
UUDAMDVQRQNNHZ-YFKPBYRVSA-N- Molecular formula
- C7H10N2O4
- Average molar mass
- 186.17 g/mol
Names & identifiers
- Preferred name
- (S)-AMPA
- English name
- (S)-AMPA
- Molecular formula
- C7H10N2O4
- Molecular weight
- 186.17
Names & synonyms
AMQ(S)-AMPAglutamate-AMPAL-AMPA, S-AMPA(S)-AMPA(S) AMPA,(S)AMPA(S)-AMPA (mM/ml)(S)-AMPA, agonist(S)-AMPA (mM/ml), AMPA agonist(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio
Database identifiers
- CAS
83643-88-3- PubChem CID
- 158397
- ChEMBL
CHEMBL276815- UNII
- 9280SC28GD
- Nikkaji
- J346.607H
Properties
Physicochemical properties
- alpha
- 28 · D28 -21 ±2° (c = 0.19 in water)
- Density
- 1.386 · 1.386±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- form
- White to off-white powder.
- pka
- 2.15 · 2.15±0.10(Predicted)
- color
- White
- Water Solubility
- 100 mM · Soluble to 100 mM in water
- InChI
- 1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
- InChIKey
- UUDAMDVQRQNNHZ-YFKPBYRVSA-N
- SMILES
- Cc1onc(O)c1C[C@H](N)C(O)=O
- CAS DataBase Reference
- 83643 · 83643-88-3(CAS DataBase Reference)
- FDA UNII
- 9280 SC28GD · 9280SC28GD
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36/37/39
- WGK Germany
- 3 · 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- risk_code
- 36/37/38
- safety_code
- 26-36/37/39
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
UsesActive enantiomer of AMPA that induces apoptosis in cortical neurons
Uses(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.
Uses(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.
General DescriptionAMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).
Suppliers33 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
Syntechem Co.,Ltd[email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
武汉凯威斯科技有限公司86-027-67849912 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
怀化市冰峰化工有限公司0745-2866851 17711757908 · [email protected]
Ascent Scientific4401179829988 · [email protected]
Related reactions
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Compound notes
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