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enoximone sulfoxide

HCID 158474
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Basic information

CAS
83982-78-9
Standard SMILES
Cc1[nH]c(=O)[nH]c1C(=O)c1ccc(S(C)=O)cc1
InChIKey
XHRYEIRXTWSXAE-UHFFFAOYSA-N
Molecular formula
C12H12N2O3S
Average molar mass
264.304 g/mol

Names & identifiers

Preferred name
enoximone sulfoxide
English name
enoximone sulfoxide
Molecular formula
C12H12N2O3S
Molecular weight
264.304

Names & synonyms

MDL-19438enoximone sulfoxide1,3-Dihydro-4-methyl-5-[4-(methylsulfinyl)benzoyl]-2H-imidazol-2-one

Database identifiers

CAS
83982-78-9
PubChem CID
158474
Nikkaji
J413.128B

Chemistry & industry

Applications · 1 item

DescriptionEnoximone sulfoxide is a selective phosphodiesterase III (PDE3) inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. Enoximone prevents the degradation of cAMP by PDE, which prolongs signal transduction and its subsequent effects. It is used in patients with congestive heart failure.

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