Basic information
- CAS
129939-63-5- Standard SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@@H](C(=O)O)C[C@H]2CCC[C@H]21- InChIKey
HDACQVRGBOVJII-ABHMUUKNSA-N- Molecular formula
- C23H32N2O5
- Average molar mass
- 416.5 g/mol
- Monoisotopic mass
- 416.23112213
Names & identifiers
- Preferred name
- (2R,3aR,6aR)-1-((2S)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
- IUPAC
- (2R,3aR,6aR)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
- English name
- (2R,3aR,6aR)-Ramipril
- Molecular formula
- C23H32N2O5
- Molecular weight
- 416.51
Names & synonyms
129939-63-5Ramipril EP Impurity N(2R,3aR,6aR)-RamiprilRamipril impurity N [EP]Ramipril isomer, (S,S,R,R,R)-MFY4AI76OW(2R,3aR,6aR)-1-((2S)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid(2R,3aR,6aR)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid(+)-Cyclopenta(b)pyrrole-2-carboxylic acid, 1-((2S)-2-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2R,3aR,6aR)-(2R,3aR,6aR)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acidCyclopenta(b)pyrrole-2-carboxylic acid, 1-((2S)-2-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2R,3aR,6aR)-UNII-MFY4AI76OW
Show more names
(2R,3αR,6αR)-RamiprilRemipril EP Impurity NRaMipril IMpurity-N(EP)Ramipril EP Impurity N HCl
Properties
Computed structural properties
- XLogP
- 1.4
- Topological polar surface area
- 95.9 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 10
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 619
Physicochemical properties
- Melting point
- 40 · 40 - 50°C
- Boiling point
- 616.166 · 616.166±55.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.201 · 1.201±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp.
- -20 °C · -20°C Freezer, Under inert atmosphere
- solubility
- Acetonitrile (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.148 · 3.148±0.20(predicted)
- color
- White to Off-White
- FDA UNII
- 4 AI76OW · MFY4AI76OW
Chemistry & industry
Applications
Uses(2R,3aR,6aR)-Ramipril (Ramipril EP Impurity N) is an isomer of the angiotensin-converting enzyme (ACE) inhibitor Ramipril (R111000). Ramipril impurity N.
UsesAn isomer of the angiotensin-converting enzyme (ACE) inhibitor Ramipril (R111000). Ramipril impurity N.
Upstream & downstream products
Upstream raw materials
Suppliers26 total
天津始加生物医药科技有限公司15022261580 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
上海尺水药物研究有限公司[email protected] 13564957716 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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