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N-[4-(4-Ethylpiperazin-1-yl)phenyl]benzo[g]quinolin-4(1H)-imine

HCID 159481
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Basic informationNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
115618-99-0
Standard SMILES
CCN1CCN(c2ccc(Nc3ccnc4cc5ccccc5cc34)cc2)CC1
InChIKey
FGVVQTVRBTWGJA-UHFFFAOYSA-N
Molecular formula
C25H26N4
Average molar mass
382.511 g/mol
Monoisotopic mass
382.21574683

Names & identifiers

Preferred name
N-[4-(4-Ethylpiperazin-1-yl)phenyl]benzo[g]quinolin-4(1H)-imine
IUPAC
N-[4-(4-Ethylpiperazin-1-yl)phenyl]benzo[g]quinolin-4(1H)-imine
English name
quinoprazine
Molecular formula
C25H26N4
Molecular weight
382.5

Names & synonyms

IND2118quinoprazineN-(4-(4-Ethylpiperazin-1-yl)phenyl)benzo[g]quinolin-4-amineBenzo[g]quinolin-4-amine, N-[4-(4-ethyl-1-piperazinyl)phenyl]-

Database identifiers

CAS
115618-99-0
PubChem CID
159481
DTXSID
DTXSID10921777
ChEMBL
CHEMBL494487

Properties

Physicochemical properties

Melting point
277 · 277-278 °C
Boiling point
585.6 · 585.6±50.0 °C(Predicted)
Density
1.203 · 1.203±0.06 g/cm3(Predicted)
pka
8.94 · 8.94±0.30(Predicted)
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
302 · H302-H315-H319-H335
Precautionary statements
270 · P270-P271-P280-P261-P264-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Safety data

Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H302-H315-H319-H335
Precautionary statements
P270-P271-P280-P261-P264-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Chemistry & industry

Applications · 1 item

UsesQuinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC50 value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrPSc levels[1]-[5].

Suppliers3 total

上海陶术生物科技股份有限公司13564774135 · [email protected]
Jilin Chinese Academy of Sciences-yanshen Technology18143011203 · [email protected]
TargetMol中国(陶术生物)15002134094 · [email protected]

Related reactions

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Compound notes

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