Temekhin
Basic information
- CAS
30015-57-7- Standard SMILES
Br.CC1(C)CC2CCN1C(C)(C)C2- InChIKey
PKYZWCLYWCKYNX-UHFFFAOYSA-N- Molecular formula
- C11H22BrN
- Average molar mass
- 248.2 g/mol
- Monoisotopic mass
- 247.09356
Overview
antihypertensive ganglionic blockader; Russian drug; structure
Names & identifiers
- Preferred name
- Temekhin
- IUPAC
- 2,2,6,6-tetramethyl-1-azabicyclo[2.2.2]octane;hydrobromide
- English name
- 2,2,6,6-Tetramethylquinicludine hydrobromide
- Molecular formula
- C11H22BrN
- Molecular weight
- 248.2
Names & synonyms
30015-57-7TemekhinTemechin2,2,6,6-tetramethylquinuclidineDTXSID60184092RefChem:187797DTXCID70106583Temechine hydrobromide2,2,6,6-Tetramethylquinuclidine hydrobromide2,2,6,6-tetramethylquinicludine hydrobromideTemechine2,2,6,6-tetramethyl-1-azabicyclo[2.2.2]octane;hydrobromide
Show more names
2,2,6,6-tetramethyl-quinuclidinhydrobromide2,2,6,6-tetramethylquinuclidinehydrobromide
TemequineQuinuclidine, 2,2,6,6-tetramethyl-, hydrobromideSCHEMBL29657518SBB080785AKOS005267165AKOS0305172862,2,6,6-tetramethylquinuclidine, bromideTemechine hydrobromide, >=98% (TLC), powder
Database identifiers
- CAS
30015-57-7- PubChem CID
- 160185
- DTXSID
DTXSID60184092- EC Number
- 636-914-7
Properties
Computed structural properties
- Topological polar surface area
- 3.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 175
Physicochemical properties
- form
- powder
- color
- colorless
- Symbol(GHS)
- 6 · GHS06
- Signal word
- Danger
- Hazard statements
- 301 · H301
- Precautionary statements
- 264 · P264-P270-P301+P310-P321-P330-P405-P501
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22
- Safety Statements
- 36 · 36
- WGK Germany
- 3 · 3
- RTECS
- 5859700 · VD5859700
- Toxicity
- 50 · mouse,LD50,intraperitoneal,345mg/kg (345mg/kg),AUTONOMIC NERVOUS SYSTEM: GAGLION BLOCKVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION,Pharmaceutical Chemistry Journal Vol. 4, Pg. 588, 1970.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 3 (100%)
Safety data
- wgk
- 3
- rtecs
- VD5859700
- Toxicity
- mouse,LD50,intraperitoneal,345mg/kg (345mg/kg),AUTONOMIC NERVOUS SYSTEM: GAGLION BLOCKVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION,Pharmaceutical Chemistry Journal Vol. 4, Pg. 588, 1970.
- risk_code
- 22
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- Xn
- safety_code
- 36
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P321-P330-P405-P501
Chemistry & industry
Applications
UsesTemechine Hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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