Pharmakon1600-01503862
Basic information
- CAS
3978-86-7- Standard SMILES
CN1CCC(=C2c3ccccc3CCc3cccnc32)CC1.O=C(O)/C=C\C(=O)O- InChIKey
KGCJWSUJYBJBBW-BTJKTKAUSA-N- Molecular formula
- C24H26N2O4
- Average molar mass
- 406.5 g/mol
- Monoisotopic mass
- 406.18925731
Names & identifiers
- Preferred name
- Pharmakon1600-01503862
- IUPAC
- (Z)-but-2-enedioic acid;2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaene
- English name
- AZATADINE MALEATE (200 MG)
- Molecular formula
- C28H30N2O8
- Molecular weight
- 522.5464
Names & synonyms
SCHEMBL450674HMS3264F05Pharmakon1600-01503862NSC759874CCG-213220Zadineidulianoptiminesch10649idinedimaleateazatadinemaleateEinecs 223-615-8
Show more names
azatadinedimaleateAZATADINE MALEATE (200 MG)AZATADINE MALEATE USP/EP/BP
Database identifiers
- CAS
3978-86-7- PubChem CID
- 16052003
Properties
Computed structural properties
- Topological polar surface area
- 90.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 2
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 536
Physicochemical properties
- Melting point
- 152 · 152-154°
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- FDA UNII
- 3 Q391WTX7 · F3Q391WTX7
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H319-H332-H317-H312
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P271-P304+P340-P312
- HS Code
- 2933399090 · 2933399090
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- hs_code
- 2933399090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H319-H332-H317-H312
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P271-P304+P340-P312
Chemistry & industry
Applications
UsesAntihistaminic.
General DescriptionAzatadine maleate, 6,11-dihydro-11-(l-methyl-4-piperidylidene)-5H-benzo-[5,6]cyclo-hepta(1,2-b]pyridine maleate (1:2) (Optimine), is a potent,long-acting antihistaminic with antiserotonin activity. Inearly testing, azatadine exhibited more than three times thepotency of chiorpheniramine in the isolated guinea pigileum screen and more than seven times the oral potency ofchlorpheniramine in protection of guinea pigs against a doublelethal dose of intravenously administered histamine.
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionChEBI: The dimaleate salt of azatadine.
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Compound notes
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