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Sodium diuranate

HCID 160982
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Basic information

CAS
13510-99-1
Standard SMILES
[Na+].[Na+].[O-2].[O-2].[O-2].[O-2].[U]
InChIKey
RDWSISWARVUWFA-UHFFFAOYSA-N
Molecular formula
Na2O4U-6
Average molar mass
348.006 g/mol
Monoisotopic mass
348.00998

Overview

Sodium uranate is a chemical compound of sodium and uranium. Uranium is a chemical element that has the symbol U and atomic number 92. It is a normal part of rocks, soil, air, and water, and occurs in nature in the form of minerals. (L248, L249)

Names & identifiers

Preferred name
Sodium diuranate
IUPAC
disodium;tetrakis(oxygen(2-));uranium
English name
disodium uranium tetraoxide
Molecular formula
Na2O4U
Molecular weight
348.00605

Names & synonyms

Sodium uranate(VI)SODIUM DIURANATESodium uranium oxide (Na2U2O7)563BIJ19PPSODIUM URANATE(VI) [MI]DISODIUM URANATE (NA2U2O7)EINECS 237-286-3URANATE (U2O72-), DISODIUMSODIUM URANATE(VI) (NA2U2O7)URANIC ACID (H2U2O7), DISODIUM SALTUranium yellowUranium oxide yellow
Show more names
Disodium uranateSodium uranium oxide
Sodium uranate (VI)RefChem:887507DTXCID901526709DTXSID701044692Disodium uranium tetraoxideEINECS 236-846-413510-99-1UNII-563BIJ19PP

Database identifiers

CAS
13510-99-1、13721-34-1
PubChem CID
160982
UNII
563BIJ19PP
EC Number
236-846-4

Properties

Computed structural properties

Topological polar surface area
4 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
4
Rotatable bonds
0
Heavy atoms
7
Formal charge
-6
Complexity
0

Experimental & physicochemical properties

Chemical ClassesPhysical/Radiation -> Radioactive Compounds

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Hazard information

Hazards SummarySee Uranium and linked occupational diseases.

Safety & protection

Exposure Control and Personal ProtectionBiological Exposure Indices (BEI) [ACGIH] - Uranium in urine = 200 ug/L at end of shift; [ACGIH]
Minimum Risk Level · 1 item

Intermediate Inhalation: 0.0004 mg/m3 (Soluble uranium salts) (L134) Chronic Inhalation: 0.0003 mg/m3 (Soluble uranium salts) (L134) Intermediate Oral: 0.002 mg/kg/day (Soluble uranium salts) (L134) Intermediate Inhalation: 0.008 mg/m3 (Insoluble uranium compounds) (L134)

Threshold Limit Values (TLV) · 2 items

0.2 [mg/m3], as U

0.6 [mg/m3], as U

Permissible Exposure Limit (PEL)0.05 [mg/m3], as U (sol), 0.25 mg/m3, as U (insol)
Immediately Dangerous to Life or Health (IDLH)10.0 [mg/m3], as U

Toxicology

Treatment · 1 item

EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.

Chemistry & industry

Pharmacology

Metabolism/Metabolites · 1 item

Uranium is absorbed in low amounts via oral, inhalation, and dermal routes. Uranium in body fluids generally exists as the uranyl ion (UO2)2+ complexed with anions, such as citrate and bicarbonate, or plasma proteins. Uranium preferentially distributes to bone, liver, and kidney. The large majority of uranium that enters the body is not absorbed and is eliminated from the body via the urine and faeces. (L248)

Uses & manufacturing

Uses · 3 items

Used to make yellow-green fluorescent glass; Used in ceramic paint and enamel; [Merck Index #8699]

Glass Manufacturing [Category: Industry]

Ceramics making [Category: Hobbies]

General Manufacturing InformationSodium uranium oxide (Na2U2O7): INACTIVE

Related reactions

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Compound notes

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Health Effects · 1 item

Uranium primarily damages the kidney, but may also damage the lungs, central nervous system, and immune system. Uranium's radioactivity is believed to damage the DNA, resulting in carcinogenic effects and reproductive and developmental damage. (L248, L249)

Exposure RoutesOral (L249) ; inhalation (L249) ; dermal (L249)
Toxicity Summary · 1 item

Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and proteins in the tubular wall, causing damage. Uranium may also inhibit both sodium transport-dependent and independent ATP utilization and mitochondrial oxidative phosphorylation in the renal proximal tubule. Uranium causes respiratory diseases by damaging alveolar epithelium type II cells in the lungs. Uranium induces c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) activation, which in turn induces tumor necrosis factor alpha (TNF-alpha) secretion and generates and inflammatory response in the lungs. Studies have shown that the more soluble the uranium salt, the more toxic it is. Ionizing radiation produced by uranium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both both initiate and promote carcinogenesis, and interfere with reproduction and development. (L249, A160)

Signs and SymptomsIngestion of uranium may cause vomiting and diarrhea. (L248)
Carcinogen ClassificationUranium: Group 1, carcinogenic to humans (L135)