Basic information
- CAS
139026-66-7- Standard SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O- InChIKey
TZCYVPLNMOJUIL-GULBXNHPSA-N- Molecular formula
- C38H66N8O7
- Average molar mass
- 747 g/mol
- Monoisotopic mass
- 746.50544645
Overview
amino acid sequence given in first source; a pseudopeptide analog of neurotensin (8-13)
Names & identifiers
- Preferred name
- Jmv 449
- IUPAC
- (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2,6-diaminohexyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
- English name
- JMV 449
- Molecular formula
- C38H66N8O7
- Molecular weight
- 746.98
Names & synonyms
Jmv 449139026-66-7Jmv-449JMV449(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2,6-diaminohexyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acidH-Lys-psi-(CH2NH)-lys-pro-tyr-ile-leu-OHNeuromedin N (pig spinal cord), 1-de-L-lysine-2-(N2-(2,6-diaminohexyl)-L-lysine)-, (S)-(2S)-2-(((2S,3S)-2-(((2S)-2-(((2S)-1-((2S)-6-amino-2-(((2S)-2,6-diaminohexyl)amino)hexanoyl)pyrrolidine-2-carbonyl)amino)-3-(4-hydroxyphenyl)propanoyl)amino)-3-methylpentanoyl)amino)-4-methylpentanoic acidRefChem:150514CID 164415KPYILH-Lysyl-psi(CH2NH)-lysyl-prolyl-tyrosyl-isoleucyl-leucine-OH
Show more names
JMV 449 TFA saltM.W. 746.96 C38H66N8O7H-LYS-(R)-LYS-PRO-TYR-ILE-LEU-OHLYS-PSI(CH2NH)-LYS-PRO-TYR-ILE-LEU(LYS8-(R)-LYS9)-NEUROTENSIN (8-13)H-Lys-psi(CH2NH)Lys-Pro-Tyr-Ile-Leu-OH[LYS8-PSI(CH2NH)-LYS9]NEUROTENSIN (8-13)
Properties
Computed structural properties
- XLogP
- -0.3
- Topological polar surface area
- 255 Ų
- Hydrogen bond donors
- 9
- Hydrogen bond acceptors
- 11
- Rotatable bonds
- 25
- Heavy atoms
- 53
- Formal charge
- 0
- Complexity
- 1,140
Physicochemical properties
- storage temp.
- -15 °C · -15°C
- form
- Powder
- Water Solubility
- 0.8 mg/ml · Soluble to 0.80 mg/ml in water
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesJMV 449 is a pseudopeptide analog of neurotensin-(8-13) with highly potent and long-lasting hypothermic and analgesic effects in the mouse.
Suppliers32 total
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
Aladdin Scientific[email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
Creative Peptides[email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
康明永瑞生物科技（苏州）有限公司17751201929 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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