Alpha-Ketoglutarate

HCID 164533

Basic information

CAS
64-15-3
Standard SMILES
O=C([O-])CCC(=O)C(=O)[O-]
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-L
Molecular formula
C5H4O5-2
Average molar mass
144.08 g/mol
Monoisotopic mass
144.00697039

Overview

2-oxoglutarate(2-) is an oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. It has a role as a geroprotector, a Saccharomyces cerevisiae metabolite, a human metabolite and an algal metabolite. It is functionally related to a glutarate(2-). It is a conjugate base of a 2-oxoglutarate(1-).

Names & identifiers

Preferred name
Alpha-Ketoglutarate
IUPAC
2-oxopentanedioate

Names & synonyms

alpha-ketoglutarate2-oxopentanedioate2 Ketoglutarate2 Oxoglutaratealpha oxoglutarateRefChem:915532ketoglutarate64-15-32-oxoglutarate(2-)2-ketoglutaratePentanedioic acid, 2-oxo-, ion(2-)2-oxopentanedionate
Show more names
2-OxoglutamatePentanedioic acid,2-oxo-, ion(2-)alphaketoglutaratealpha-oxoglutarate2xzw3hww2-oxopentanedionic acid4-Carboxy-2-oxo-butyrate

Database identifiers

CAS
64-15-3
PubChem CID
164533
DTXSID
DTXSID80213974
ChEBI
CHEBI:16810
Nikkaji
J1.181.515D

Properties

Computed structural properties

XLogP
0.4
Topological polar surface area
97.3 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
5
Rotatable bonds
2
Heavy atoms
10

Related reactions

35 records

Compound notes

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