[2,2'-Biquinoline]-4,4'-dicarboxylic acid, sodium salt (1:2)
Basic information
- CAS
979-88-4- Standard SMILES
O=C([O-])c1cc(-c2cc(C(=O)[O-])c3ccccc3n2)nc2ccccc12.[Na+].[Na+]- InChIKey
AUPXFICLXPLHBB-UHFFFAOYSA-L- Molecular formula
- C20H10N2Na2O4
- Average molar mass
- 388.3 g/mol
- Monoisotopic mass
- 388.04359537
Names & identifiers
- Preferred name
- [2,2'-Biquinoline]-4,4'-dicarboxylic acid, sodium salt (1:2)
- IUPAC
- disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-4-carboxylate
- English name
- Bicinchoninic Acid Disodium Salt
- Molecular formula
- C20H13N2NaO4
- Molecular weight
- 368.32
Names & synonyms
979-88-4[2,2'-Biquinoline]-4,4'-dicarboxylic acid, disodium salt(2,2'-Biquinoline)-4,4'-dicarboxylic acid, disodium saltDTXSID2061357(2,2'-Biquinoline)-4,4'-dicarboxylic acid, sodium salt (1:2)[2,2'-Biquinoline]-4,4'-dicarboxylic acid, sodium salt (1:2)RefChem:205310DTXCID9049039Sodium [2,2'-biquinoline]-4,4'-dicarboxylateBCA Disodiumbicinchoninic acid disodium saltDisodium 2,2'-biquinoline-4,4'-dicarboxylate
Show more names
BICINCHONINIC ACID DISODIUM SALT HYDRATEBCA-2NaBicinchonic acidSodiumBicinchoniateBCA DISODIUM SALTBicinchoninic acid hDisodium bicinchoninate
2,2'-Biquinoline-4,4'-dicarboxylic acid disodium saltBCADisodiumBCAMFCD00037500AKOS015951447DISODIUM [2,2'-BIQUINOLINE]-4,4'-DICARBOXYLATESodiumBicinchoninateB4509
Database identifiers
- CAS
979-88-4- PubChem CID
- 164763
- DTXSID
DTXSID2061357- ChEMBL
CHEMBL222564- EC Number
- 629-761-2
- Nikkaji
- J1.002.885J
Properties
Computed structural properties
- Topological polar surface area
- 106 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 1
- Heavy atoms
- 28
- Formal charge
- 0
- Complexity
- 495
Physicochemical properties
- Melting point
- 300 ℃ · 300℃
- storage temp.
- 2 · Inert atmosphere,2-8°C
- solubility
- 0.5 % · 0.5% sodium bicarbonate: soluble50mg/mL
- form
- Powder/Chunks
- color
- white to light yellow
- Water Solubility
- Soluble in water.
- Stability
- Hygrscopic
- Major Application
- diagnostic assay manufacturinghematologyhistology
- InChI
- InChI=1S/C20H12N2O4.Na.H/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);;
- InChIKey
- AUPXFICLXPLHBB-UHFFFAOYSA-L
- SMILES
- C(C1=CC(C2=NC3=CC=CC=C3C(C(=O)O)=C2)=NC2=CC=CC=C12)(=O)O.[NaH]
- CAS DataBase Reference
- 979 · 979-88-4(CAS DataBase Reference)
- EPA Substance Registry System
- 2 · [2,2'-Biquinoline]-4,4'-dicarboxylic acid, disodium salt (979-88-4)
- UNSPSC Code
- 12171500 · 12171500
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 9 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
[2,2'-Biquinoline]-4,4'-dicarboxylic acid, disodium salt: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29339900
- risk_code
- 36/37-42-36/38-36/37/38-20/21/22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn,Xi
- safety_code
- 22-26-36/37-45-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319
- Hazard Classifications
Chemistry & industry
Uses & manufacturing
General Manufacturing Information[2,2'-Biquinoline]-4,4'-dicarboxylic acid, sodium salt (1:2): ACTIVE
Applications
Description2,2’-Biquinoline-4,4’-dicarboxylic acid (BCA) is a colorimetric reagent for the detection of copper (Cu+). BCA and Cu+ form a stable 2:1 complex that has an absorbance maximum at 562 nm. It is commonly used as a reagent in the colorimetric BCA protein quantitation assay in which Cu2+ is converted to Cu+ as a function of protein concentration under alkaline conditions.
UsesBicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases. It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose). It has been used for determining protein concentration.
UsesFor determination of Cu and protein assays.Bicinchoninic acid disodium salt is useful for the determination of copper. It is also used for the determination of protein concentration.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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