HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-CRESYL GLYCIDYL ETHER
2-Methylphenyl glycidyl ether · DY 023 · Nsc11571 · o-cresyl · Heloxy 62 · Epodil 742 · aralditedy023 · 2-((o-Tolyloxy)
Identifiers & Physical Properties
| CAS No. | 2210-79-9 |
|---|---|
| Molecular formula | C10H12O2 |
| Average molar mass | 164.2 g/mol |
| Monoisotopic mass | 164.08372962 g/mol |
| SMILES | Cc1ccccc1OCC1CO1 |
| InChIKey | KFUSXMDYOPXKKT-UHFFFAOYSA-N |
| PubChem CID | 16640 |
| ChEMBL | CHEMBL1445408 |
| EC No. | 218-645-3 |
| DTXSID | DTXSID8024862 |
Chemical & Physical Properties
| XLogP | 2.4 |
|---|---|
| Topological polar surface area | 21.8 |
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 2 |
| Rotatable bonds | 3 |
| Heavy atoms | 12 |
| Formal charge | 0 |
| Complexity | 147 |
| Polymers | Plastics & Rubber -> Glycidyl Ethers |
| Density | 1.09 at 68 °F (NTP, 1992) - Denser than waterwill sinkRelative density (water = 1): 1.081.079 g/mL at 25 °C (lit.) |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992)Solubility in water: none840mg/L at 21℃ |
| Flash point | 200 °F (NTP, 1992)113 °C c.c.>230 °F |
| Boiling point | 498 °F at 760 mmHg (NTP, 1992)at 0.533kPa: 109-111 °C109-111 °C/4 mmHg (lit.) |
| Vapor density | Relative vapor density (air = 1): 5.7>1 (vs air) |
| Physical Description | O-cresyl glycidyl ether is a clear light yellow liquid. (NTP, 1992)Clear light yellow liquid[CAMEO]COLOURLESS LIQUID. |
| Vapor pressure | 0.514Pa at 20℃ |
| Refractive index | n20/D 1.529(lit.) |
| Physical state | liquid |
| BRN | 4585 |
| InChI | InChI=1S/C10H12O2/c1-8-4-2-3-5-10(8)12-7-9-6-11-9/h2-5,9H,6-7H2,1H3 |
| InChIKey | KFUSXMDYOPXKKT-UHFFFAOYSA-N |
| SMILES | O1CC1COC1=CC=CC=C1C |
| LogP (partition coefficient) | 2.5 at 21℃ |
| CAS DataBase Reference | 2210-79-9(CAS DataBase Reference) |
| EWG's Food Scores | 2-3 |
| FDA UNII | 8Z744RD471 |
| NIST Chemistry Reference | Oxirane, [(2-methylphenoxy)methyl]-(2210-79-9) |
| EPA Substance Registry System | o-Cresyl glycidyl ether (2210-79-9) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
| GHS pictogram | GHS07,GHS08,GHS09 |
| Signal word | Warning |
| GHS hazard statements | H315-H317-H341-H411 |
| GHS precautionary statements | P202-P261-P273-P280-P302+P352-P308+P313 |
| Personal protective equipment (PPE) | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard symbols | Xi,N,Xn |
| Risk statements (R) | 36/37/38-68-51/53-43-38 |
| Safety statements (S) | 26-37/39-61-36/37 |
| UN transport number | UN 3082 9/PG 3 |
| Water hazard class (WGK) | 2 |
| RTECS number | TZ3700000 |
| TSCA inventory status | TSCA listed |
| Hazard class | 9Aquatic Chronic 2Muta. 2Skin Irrit. 2Skin Sens. 1A |
| Packing group | III |
| Customs code | 29109000 |
| Storage class | 10 - Combustible liquids |
| REACH registrations | Active |
Safety & Regulations
| GHS classification | WarningH315: Causes skin irritation [Warning Skin corrosion/irritation]P203, P261, P264, P272, P273, P280, P302+P352, P318, P321, P332+P317, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
|---|---|
| Regulatory information | Chemical: Oxirane, [(2-methylphenoxy)methyl]-Oxirane, 2-[(2-methylphenoxy)methyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-[(2-methylphenoxy)methyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.Status: Active Update: 05-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14553Oxirane, [(2-methylphenoxy)methyl]-: Does not have an individual approval but may be used under an appropriate group standard |
| Other safety information | IMAP assessments - Oxirane, [(2-methylphenoxy)methyl]-: Environment tier I assessment |
| DOT label | Class 9 |
| Fire hazards | This chemical is combustible. (NTP, 1992) |
| Health hazards | SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and eyes, and allergic dermatitis. |
| Hazards summary | May cause skin sensitization[ICSC] Danger of skin sensitization[MAK] |
| Reactive group | Ethers |
| EC classification | Symbol: Xn, NR: 38-43-68-51/53S: (2)-36/37-61Note: C |
| Reactivity Profile | O-CRESYL GLYCIDYL ETHER may attack some forms of plastics. (NTP, 1992) |
| Chemical Dangers | The substance can presumably form explosive peroxides. Reacts with acids, amines, bases and strong oxidants. |
| Air and Water Reactions | Insoluble in water. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%)Skin irritation - category 2Serious eye damage/eye irritation - Category 2BSkin sensitization - Category 1ASkin corrosion/irritation - Category 2Muta. 2 |
| Fire fighting | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)Use water spray, foam, powder, carbon dioxide. |
| First aid measures | Fresh air, rest.Remove contaminated clothes. Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. |
| First aid | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Safe storage | Separated from strong oxidants, strong bases, strong acids and amines. Cool. Keep in the dark. |
| Nonfire spill response | SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Spillage disposal | Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. |
| Isolation and Evacuation | Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: |
| Eye Prevention | Wear safety goggles or eye protection in combination with breathing protection. |
| Fire Prevention | NO open flames. |
| Inhalation Risk | No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C. |
| Skin Prevention | Protective gloves. Protective clothing. |
| Exposure Prevention | AVOID ALL CONTACT! |
| Adverse effects | Skin Sensitizer - An agent that can induce an allergic reaction in the skin. |
| Signs and Symptoms | Cough. Sore throat.Redness. Pain. |
| Toxicity Data | LC50 (rat) = 6,090 mg/m3/4h |
| Personal protective equipment (PPE) | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Water hazard class (WGK) | 2 |
| TSCA inventory status | TSCA listed |
| RTECS number | TZ3700000 |
| UN transport number | UN 3082 9/PG 3 |
| Customs code | 29109000 |
| Risk statements (R) | 36/37/38-68-51/53-43-38 |
| Signal word | Warning |
| GHS pictogram | GHS07,GHS08,GHS09 |
| Hazard symbols | Xi,N,Xn |
| Safety statements (S) | 26-37/39-61-36/37 |
| Hazard class | 9Aquatic Chronic 2Muta. 2Skin Irrit. 2Skin Sens. 1A |
| Storage class | 10 - Combustible liquids |
| Packing group | III |
| GHS hazard statements | H315-H317-H341-H411 |
| REACH registrations | Active |
| GHS precautionary statements | P202-P261-P273-P280-P302+P352-P308+P313 |
Applications & Uses
General Description
Clear light yellow liquid.