(R)-2-(3-((3-Fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)isoindoline-1,3-dione

Linezolid DesacetaMide Descarbonyl PhthaliMide · Linazolid intermediate · Linezolid impurity INT1 · Linezolid impurity INT1 reference substance · (R)-Linezolid Desacetamide Descarbonyl Phthalimide · Linezolid Desacetamide Descarbonyl Phthalimide (R)-Isomer · N-(3-PhthaliMido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline · N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(4-morpholinyl)aniline

https://huagongshe.com/en/chemical/16655949

(R)-2-(3-((3-Fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)isoindoline-1,3-dione molecular structure

Identifiers & Physical Properties

CAS No.	874340-08-6
Molecular formula	C21H22FN3O4
Average molar mass	399.4 g/mol
Monoisotopic mass	399.1594344 g/mol
SMILES	O=C1c2ccccc2C(=O)N1C[C@H](O)CNc1ccc(N2CCOCC2)c(F)c1
InChIKey	UVDYUDNYSNKZRV-OAHLLOKOSA-N
PubChem CID	16655949
ChEBI	CHEBI:181268
DTXSID	DTXSID70586523

Chemical & Physical Properties

XLogP	1.8
Topological polar surface area	82.1
Hydrogen bond donors	2
Hydrogen bond acceptors	7
Rotatable bonds	6
Heavy atoms	29
Formal charge	0
Complexity	576
Melting point	155-156 °C
Density	1.397
Storage conditions	Refrigerator
Solubility	Chloroform (Slightly), Ethanol (Slightly), Methanol
Physical state	Solid
Color	Orange to Dark Orange
InChI	InChI=1S/C21H22FN3O4/c22-18-11-14(5-6-19(18)24-7-9-29-10-8-24)23-12-15(26)13-25-20(27)16-3-1-2-4-17(16)21(25)28/h1-6,11,15,23,26H,7-10,12-13H2/t15-/m1/s1
InChIKey	UVDYUDNYSNKZRV-OAHLLOKOSA-N
SMILES	C1(=O)C2=C(C=CC=C2)C(=O)N1C[C@H](O)CNC1=CC=C(N2CCOCC2)C(F)=C1
GHS pictogram	GHS07
Signal word	Warning
GHS hazard statements	H302-H315-H319-H335
GHS precautionary statements	P280-P305+P351+P338

Safety & Regulations

Signal word	Warning
GHS pictogram	GHS07
GHS hazard statements	H302-H315-H319-H335
GHS precautionary statements	P280-P305+P351+P338

Applications & Uses

Uses

Linezolid (L466500) intermediate. Linezolid is a prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.