Basic information
- CAS
2217-41-6- Standard SMILES
Nc1cccc2c1CCCC2- InChIKey
SODWJACROGQSMM-UHFFFAOYSA-N- Molecular formula
- C10H13N
- Average molar mass
- 147.22 g/mol
- Monoisotopic mass
- 147.10479942
Names & identifiers
- Preferred name
- 5-Tetralinylamine
- IUPAC
- 5,6,7,8-tetrahydronaphthalen-1-amine
- English name
- 5,6,7,8-Tetrahydro-1-naphthylamine
- Molecular formula
- C10H13N
- Molecular weight
- 147.22
Names & synonyms
5,6,7,8-Tetrahydro-1-naphthylamine2217-41-65-Aminotetralin1-Amino-5,6,7,8-tetrahydronaphthalene5-Tetralylamine1-Naphthalenamine, 5,6,7,8-tetrahydro-5,6,7,8-Tetrahydro-1-naphthalenamine5-Amino-1,2,3,4-tetrahydronaphthalene1-NAPHTHYLAMINE, 5,6,7,8-TETRAHYDRO-5-Tetralinylaminealpha-TetrahydronaphthylamineNSC 53503
Show more names
Tetralin-5-amineAKOS BBS-00003705TIMTEC-BB SBB0040915,6,7,8-Tetrahydro-1Tetrahydro-1-naphthylaM
EINECS 218-713-2BRN 0387264U0L74S8K6GNSC-535031,2,3,4-Tetrahydro-5-naphthylamine1,2,3,4-Tetrahydro-5-naphthalenamineDTXSID701767014-12-00-02934 (Beilstein Handbook Reference)
Database identifiers
- CAS
2217-41-6- PubChem CID
- 16671
- DTXSID
DTXSID70176701- UNII
- U0L74S8K6G
- EC Number
- 218-713-2
- Nikkaji
- J42.466H
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 26 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 133
Experimental & physicochemical properties
SpringerMaterials PropertiesViscosity
Physicochemical properties
- Melting point
- 38 °C · 38 °C(lit.)
- Boiling point
- 275 · 275-277 °C713 mm Hg(lit.)
- Density
- 1 · 1,06 g/cm3
- refractive index
- 20 · n20/D 1.590(lit.)
- Flash point
- 230 °F · >230 °F
- solubility
- miscible with Alcohol
- form
- Liquid
- pka
- 4.56 · 4.56±0.20(Predicted)
- color
- Clear yellow to brown
- BRN
- 387264 · 387264
- InChI
- 1S/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7H,1-2,4,6,11H2
- InChIKey
- SODWJACROGQSMM-UHFFFAOYSA-N
- SMILES
- Nc1cccc2CCCCc12
- CAS DataBase Reference
- 2217 · 2217-41-6(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 0 L74S8K6G · U0L74S8K6G
- NIST Chemistry Reference
- 1 · 1-Naphthalenamine, 5,6,7,8-tetrahydro-(2217-41-6)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302+H312+H332-H315-H319-H335
- Precautionary statements
- 501 · P501-P270-P261-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P233-P405
- PPE
- Eyeshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36
- WGK Germany
- 3 · 3
- RTECS
- 4780000 · QM4780000
- F
- 9 · 9
- HS Code
- 29214990 · 29214990
- Storage Class
- 10 · 10 - Combustible liquids
Safety & regulation
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: 1-Naphthalenamine, 5,6,7,8-tetrahydro-
1-Naphthalenamine, 5,6,7,8-tetrahydro-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- F
- 9
- PPE
- Eyeshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- rtecs
- QM4780000
- hs_code
- 29214990
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Storage Class
- 10 - Combustible liquids
- Hazard statements
- H302+H312+H332-H315-H319-H335
- Precautionary statements
- P501-P270-P261-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P233-P405
Chemistry & industry
Applications
Uses5,6,7,8-Tetrahydro-1-naphthylamine is used as a reagent in the synthesis of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels. 5,6,7,8-Tetrahydro-1-naphthylamine is also used as a reagent in the synthesis of benzopyrans and related compounds as inhibitors of the hypoxia inducible factor pathway.
Upstream & downstream products
Downstream products
Suppliers87 total
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
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Related reactions
61 records
Compound notes
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